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  • 2005-2009  (3)
  • 1
    Publication Date: 2022-05-25
    Description: Author Posting. © Elsevier B.V., 2006. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Progress In Oceanography 70 (2006): 91-112, doi:10.1016/j.pocean.2006.07.002.
    Description: Gabriel T. Csanady turned 80 in December 2005 and we celebrate it with this special Progress in Oceanography issue. It comprises 20 papers covering some of the many areas that Gabe contributed significantly throughout his professional career. In this introductory paper we briefly review Gabe’s career as an engineer, meteorologist and oceanographer, and highlight some of his major contributions to oceanography, both as a scientist as well as an educator. But we also use this opportunity to remember and thank Gabe, and his wife Joyce, for being such good friends and mentors to several generations of oceanographers. The authors of the collection of papers in this volume deserve special thanks for their efforts. We also are pleased to acknowledge the support of Progress in Oceanography’s editor, Detlef Quadfasel, and the many anonymous reviewers who generously contributed their time and expertise.
    Keywords: Csanady ; Oceanographer ; Biography ; Ocean circulation ; Turbulent diffusion ; Air-sea interaction
    Repository Name: Woods Hole Open Access Server
    Type: Preprint
    Format: 819031 bytes
    Format: application/pdf
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  • 2
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background and objective The thromboxane A2 receptor (TBXA2R) is a receptor for a potent bronchoconstrictor, TBXA2 which is known to be related to bronchial asthma and myocardial infarction. TBXA2R antagonist and TBX synthase inhibitors have been found to be effective in the management of asthmatic patients. This study was aimed to evaluate whether genetic variants of TBXA2R may be related with development of acetyl salicylic acid (ASA)-intolerant asthma (AIA).Methods TBXA2R gene polymorphisms (TBXA2R+795T〉C, TBXA2R+924T〉C) were determined using a single-base extension method in 93 AIA patients compared with 172 patients with ASA-tolerant asthma (ATA) and 118 normal controls (NCs) recruited from the Korean population. HLA DPB1*0301 genotype was performed using a direct sequencing method.Results The rare C allele frequency of TBXA2R+795T〉C was significantly higher in AIA than in ATA (P=0.03) and the TBXA2R+795T〉C polymorphism was also associated with extent of percent fall in forced expiratory volume in 1 s (FEV1) after the inhalation of lysine–acetyl salicylic acid in AIA patients (P=0.009); AIA patients homozygous for the +795 C allele had a greater percent fall of FEV1 compared with individuals with TBXA2R+795 CT or TT genotypes. The frequency of patients carrying both the TBXA2R+795T〉C rare allele and HLA DPB1*0301 was significantly higher in AIA patients (29.4%) than in ATA patients (7.3%) (P=0.008, odds ratio=5.3).Conclusion These results suggest that the polymorphism of TBXA2R+795T〉C may increase bronchoconstrictive response to ASA, which could contribute to the development of the AIA phenotype.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 442 (2006), S. 1021-1024 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Nuclear magnetic resonance (NMR) in liquids and solids is primarily detected by recording the net dipolar magnetic field outside the spin-polarized sample. But the recorded bulk magnetic field itself provides only limited spatial or structural information about the sample. Most NMR applications ...
    Type of Medium: Electronic Resource
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