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  • 1
    Online Resource
    Online Resource
    London :Elsevier Health Sciences,
    Keywords: Respiratory Physiological Phenomena. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (180 pages)
    Edition: 2nd ed.
    ISBN: 9780702050725
    Series Statement: Systems of the Body Series
    DDC: 611.2
    Language: English
    Note: Front cover -- The respiratory system: Basic science and clinical conditions -- Copyright page -- Preface -- Acknowledgements -- Contents -- CHAPTER 1 INTRODUCTION -- Introduction -- What is respiration? -- The need for respiration -- Diffusion in respiration and the circulation -- Timing in the circulation and respiration -- Basic science of respiration -- Drugs -- CHAPTER 2 STRUCTURE OF THE RESPIRATORY SYSTEM, RELATED TO FUNCTION -- Introduction -- The upper airways -- The intrathoracic airways -- Blood vessels -- Pulmonary hypertension -- The lymphatics -- The nerves -- Gross structure of the respiratory system -- Pleurisy -- The diaphragm and chest wall -- How breathing is brought about -- Embryology -- Air-conditioning -- Metabolic activity -- Metabolism of circulating biologically active substances -- Non-respiratory functions -- CHAPTER 3 ELASTIC PROPERTIES OF THE RESPIRATORY SYSTEM -- Introduction -- Intrapleural pressure (P[sub(pl)]) -- Static lung compliance (C[sub(L)]) -- The effect of disease -- The physical basis of lung compliance -- CHAPTER 4 AIRFLOW IN THE RESPIRATORY SYSTEM -- Introduction -- How airflow is brought about -- The nature of airflow -- The major determinant of flow - radius -- Airways resistance and obstructive pulmonary disease -- The clinical situation -- Sites of airways resistance -- Asthma and airways smooth muscle -- Bronchomotor tone -- Pharmacological treatment of asthma -- Clinical definitions -- Bronchitis and mucus -- Emphysema and radial traction -- Intrapleural pressure and cough -- Clinical tests for changes in resistance -- Work of breathing -- CHAPTER 5 VENTILATION OF THE RESPIRATORY SYSTEM: THE IMPORTANCE OF ITS LACK OF UNIFORMITY IN DISEASE -- Introduction -- Spirometric abnormalities in disease -- Uneven distribution -- Dead space -- Alveolar dead space in disease -- The Bohr equation. , Factors affecting physiological dead space -- Alveolar ventilation and respiratory exchange -- The alveolar gas equation -- Distribution of inspired gas -- Other factors in. uencing distribution -- CHAPTER 6 GAS EXCHANGE BETWEEN AIR AND BLOOD: DIFFUSION -- The path from air to tissue -- Lung disease and diffusion -- Fick's Law of Diffusion -- Measuring transfer factor -- Treating diffusion difficulties -- Carbon dioxide and other gases -- CHAPTER 7 THE PULMONARY CIRCULATION: BRINGING BLOOD AND GAS TOGETHER -- The functions of the pulmonary circulation -- The anatomy of the pulmonary circulation -- Matching ventilation and perfusion -- Distribution of blood flow through the lungs -- Regional differences in ventilation in the lungs -- Ventilation/perfusion matching and its effect on blood O[sub(2)] and CO[sub(2)] content -- Shunt -- CHAPTER 8 CARRIAGE OF GASES BY THE BLOOD AND ACID/BASE BALANCE -- Introduction -- Oxygen transport -- Dissolved oxygen: do we really need Hb and why keep it in red cells? -- Carbon dioxide transport -- Acid-base balance -- CHAPTER 9 CHEMICAL CONTROL OF BREATHING -- Introduction -- Oxygen lack -- Carbon dioxide excess -- CHAPTER 10 NERVOUS CONTROL OF BREATHING -- Introduction -- The rhythm generator -- Pattern of breathing in COPD -- The respiratory 'centres' -- The medullary groups -- Conscious control of breathing -- Respiratory muscle innervation -- Neuromuscular disorders -- Vagal reflexes -- Dyspnoea -- Other reflexes -- CHAPTER 11 LUNG FUNCTION TESTS: MEASURING DISABILITY -- Introduction -- Spirometry -- Flow measurements -- Plethysmography -- Lung mechanics -- Transfer factor (diffusing capacity) -- Blood gases -- Gas washouts -- Exercise testing -- Challenge tests -- Appendix: some basic science -- Glossary -- A -- B -- C -- D -- E -- F -- G -- H -- I -- L -- M -- P -- R -- S -- T -- V -- W -- Index -- A -- B -- C. , D -- E -- F -- G -- H -- I -- K -- L -- M -- N -- O -- P -- R -- S -- T -- U -- V -- W -- X.
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  • 2
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    PANGAEA
    In:  Supplement to: Yesson, Chris; Taylor, Michelle L; Tittensor, Derek P; Davies, Andrew; Guinotte, John M; Baco, Amy R; Black, Julie; Hall-Spencer, Jason M; Rogers, Alex David (2012): Global habitat suitability of cold-water octocorals. Journal of Biogeography, 39(7), 1278-1292, https://doi.org/10.1111/j.1365-2699.2011.02681.x
    Publication Date: 2024-02-17
    Description: This dataset consists of global raster maps indicating the habitat suitability for 7 suborders of cold water octocorals (Octocorallia found deeper than 50m). Maps present a relative habitat suitability index ranging from 0 (unsuitable) to 100 (highly suitable). Two maps are provided for each suborder (Alcyoniina, Calcaxonia, Holaxonia, Scleraxonia, Sessiliflorae, Stolonifera, and Subselliflorae). A publicly accessable low resolution map (grid size 10x10 arc-minutes) and a restricted access high resolution map (grid size 30x30 arc-seconds). Maps are geotiff format incorporating LZW compression to reduce file size. Please contact the corresponding author (Chris Yesson) for access to the high resolution data.
    Keywords: CoralFISH; Ecosystem based management of corals, fish and fisheries in the deep waters of Europe and beyond
    Type: Dataset
    Format: unknown
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  • 3
    Publication Date: 2017-05-09
    Description: Anthropogenic litter is present in all marine habitats, from beaches to the most remote points in the oceans. On the seafloor, marine litter, particularly plastic, can accumulate in high densities with deleterious consequences for its inhabitants. Yet, because of the high cost involved with sampling the seafloor, no large-scale assessment of distribution patterns was available to date. Here, we present data on litter distribution and density collected during 588 video and trawl surveys across 32 sites in European waters. We found litter to be present in the deepest areas and at locations as remote from land as the Charlie-Gibbs Fracture Zone across the Mid-Atlantic Ridge. The highest litter density occurs in submarine canyons, whilst the lowest density can be found on continental shelves and on ocean ridges. Plastic was the most prevalent litter item found on the seafloor. Litter from fishing activities (derelict fishing lines and nets) was particularly common on seamounts, banks, mounds and ocean ridges. Our results highlight the extent of the problem and the need for action to prevent increasing accumulation of litter in marine environments.
    Type: Article , PeerReviewed
    Format: text
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  • 4
    Publication Date: 2012-01-01
    Description: Changes in the possible behavior of El Niño–Southern Oscillation (ENSO) with global warming have provoked interest in records of ENSO from past “greenhouse” climate states. The latest Cretaceous laminated Marca Shale of California permits a seasonal-scale reconstruction of water column flux events and hence interannual paleoclimate variability. The annual flux cycle resembles that of the modern Gulf of California with diatoms characteristic of spring upwelling blooms followed by silt and clay, and is consistent with the existence of a paleo–North American Monsoon that brought input of terrigenous sediment during summer storms and precipitation runoff. Variation is also indicated in the extent of water column oxygenation by differences in lamina preservation. Time series analysis of interannual variability in terrigenous sediment and diatom flux and in the degree of bioturbation indicates strong periodicities in the quasi-biennial (2.1–2.8 yr) and low-frequency (4.1–6.3 yr) bands both characteristic of ENSO forcing, as well as decadal frequencies. This evidence for robust Late Cretaceous ENSO variability does not support the theory of a “permanent El Niño,” in the sense of a continual El Niño–like state, in periods of warmer climate.
    Print ISSN: 0091-7613
    Electronic ISSN: 1943-2682
    Topics: Geosciences
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  • 5
    Publication Date: 2013-10-26
    Description: Labeling nonquiescent cells with carboxyfluorescein succinimidyl ester (CFSE)-like dyes gives rise to a population width exceeding the threshold for resolving division peaks by flow cytometry. Width is a function of biological heterogeneity plus extrinsic and intrinsic error sources associated with the measurement process. Optimal cytometer performance minimizes extrinsic error, but reducing intrinsic error to the point of facilitating peak resolution requires careful fluorochrome selection and fluorescent cell sorting. In this study, we labeled the Jurkat and A549 cell lines with CFSE, CellTraceViolet (CTV), and eFluor 670 proliferation dye (EPD) to test if we could resolve division peaks in culture after reducing the labeled input widths by cell sorting. Reanalysis of the sorted populations to ascertain the level of reduction achieved always led to widths exceeding the gated limits due to the contribution of errors. Measuring detector-specific extrinsic error by sorting uniform fluorescent particles with similar spectral properties to the tracking dyes allowed us to determine the intrinsic error for each dye and cell type using a simple mathematical approach. We found that cell intrinsic error ultimately dictated whether we could resolve division peaks, and that as this increased, the required sort gate width to resolve any division peaks decreased to the point whereby issues with yield made A549 unsuitable for this approach. Finally, attempts to improve yields by setting two concurrent sort gates on the fluorescence distribution enriched for cells in different stages of the cell cycle that had nonequivalent proliferative properties in culture and thus should be practiced with caution. © 2013 International Society for Advancement of Cytometry
    Electronic ISSN: 1552-4930
    Topics: Biology , Medicine
    Published by Wiley-Blackwell
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  • 6
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    Elsevier
    Publication Date: 2014-12-31
    Description: The Authors Reply: Kidney International 87, 240 (January 2015). doi:10.1038/ki.2014.311 Authors: Simon J Davies & Andrew Davenport
    Topics: Medicine
    Published by Elsevier
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  • 7
    Publication Date: 2014-08-30
    Description: The role of bioimpedance and biomarkers in helping to aid clinical decision-making of volume assessments in dialysis patients Kidney International 86, 489 (September 2014). doi:10.1038/ki.2014.207 Authors: Simon J Davies & Andrew Davenport
    Keywords: blood pressurechronic inflammationheart failurehemodialysisperitoneal dialysis
    Topics: Medicine
    Published by Elsevier
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