ISSN:
1600-5724
Source:
Crystallography Journals Online : IUCR Backfile Archive 1948-2001
Topics:
Chemistry and Pharmacology
,
Geosciences
,
Physics
Notes:
The influence of hydrogen/deuterium exchange on the intensity scattered by solutions of globular particles in neutron small-angle scattering experiments in 2H2O/1H2O buffers has been calculated. By separating the contribution of the change of the average scattering density of the solute from that of the inhomogeneities of the distribution of exchangeable hydrogens, equations similar to the classical equations of Stuhrman & Kirste [Z. Phys. Chem. (Frankfurt am Main) (1965), 46, 247-250] and Ibel & Stuhrman [J. MoI. Biol. (1975), 93, 255-265] are obtained. But the equations contain a contribution from the contrast-dependent fluctuations, and the geometrical parameters of the particle can no longer be simply extracted from a contrast variation study, if exchangeable hydrogens are not homogeneously distributed throughout the particle. Several examples are discussed and the potentialities of contrast variation in neutron and X-ray small-angle scattering" are compared.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1107/S0108767383001427
