ISSN:
1438-2199
Keywords:
Amino acids
;
N-(Carboxyalkyl)amino acids
;
N6-(Carboxymethyl)lysine
;
N5-(carboxymethyl)ornithine
;
Lactococcus lactis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary This report describes the enzyme-catalyzed synthesis, characterization, and chromatographic separation of N6-(carboxymethyl)-L-lysine and N5-(carboxymethyl)-L-ornithine. The two N ω -(carboxyalkyl)amino acids are formed via a reductive condensation between glyoxylate and theε- orδ-amino groups of lysine and ornithine, respectively. Both reactions are catalyzed by the NADPH-dependent enzyme, N5-(carboxyethyl)ornithine synthase [EC 1.5.1.24], found in some strains of the lactic acid bacteriumLactococcus lactis subsp.lactis.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00805846
