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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 83 (1975), S. 151-162 
    ISSN: 1432-1335
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Gewebe enthalten ein Enzym, das Bleomycin (BLM) inaktiviert. Die Enzymaktivität ist in Extrakten aus verschiedenen Geweben unterschiedlich hoch. In der vorliegenden Arbeit wird eine Methode zur Bestimmung der BLM-inaktivierenden Enzymaktivität aus Organen und Geweben von Mäusen beschrieben. Diese BLM-inaktivierende Enzymaktivität ist in Extrakten aus Leber am höchsten, Hoden, Milz, Lunge und Gehirn weisen geringere Aktivitäten auf; in Hautgewebe fehlt dieses Enzym fast völlig.
    Notes: Summary An enzyme that inactivates bleomycin (BLM) can be extracted from tissue. The activity of this enzyme varies markedly in different tissues. In the present paper, a method is described by which the activity of the BLM-inactivating enzyme in different organs and tissues of mice can be determined. The highest activity is found in liver; lower enzyme concentrations occur in the testis, spleen, lung and brain. In skin this enzyme is almost completely missing.
    Type of Medium: Electronic Resource
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