ISSN:
1573-6822
Keywords:
dendritic cells
;
immunity
;
Langerhans cells
;
skin
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Human skin constitutes the first immune defense barrier. Among the epidermal cells, the Langerhans cells, which belong to the dendritic cells, represent the pivotal cells in cutaneous immune reactions. The possibility of obtaining human Langerhans cells either from human skin or by in vitro generation from CD34+ hematopoietic precursors opens the way to studies reproducing the successive steps of the Langerhans cells' role in contact dermatitis.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1007550606437