ISSN:
0941-1216
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Acyclic Stereochemical Analysis. III. Estimation of the Preferred Conformers of Substituted γ-Chloropropyl-methyl Ethers by NMR Spectroscopy and Molecular ModellingThe conformers of the various stereoisomers of a series of γ-chloropropyl methyl ethers 1-4 with 1, 2 and 3 chiral centres have been estimated by Molecular Modelling (MOBY) and the results compared with the data of previous 1H and 13C NMR studies. The calculations corroborate former NMR results and the remarkable potential of both NMR spectroscopy and Molecular Modelling to assign even four diastereomers of acyclic molecules with three chiral centres.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19933350808