Keywords:
Alkaloids -- Physiological effect.
;
Alkaloids.
;
Electronic books.
Type of Medium:
Online Resource
Pages:
1 online resource (389 pages)
Edition:
1st ed.
ISBN:
9780080865454
Series Statement:
Issn Series
URL:
https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=405444
Language:
English
Note:
Front Cover -- The Alkaloids: Chemistry and Pharmacology -- Copyright Page -- Contents -- List of Contributors -- Preface -- Contents of Previous Volumes -- Chapter 1. Acridone Alkaloids: Experimental Antitumor Activity of Acronycine -- I. Historical Introduction -- II. Physical and Chemical Properties -- III. Structure of Acronycine: Principal Syntheses -- IV. Experimental Antitumor Activity of Acronycine -- V. Structure-Activity Relationships (SAR) -- VI. Mammalian Metabolism -- VII. Preclinical Studies of Acronycine -- VIII. Mechanism of Action -- IX. Summary and Conclusions -- Appendix -- Addendum -- References -- Chapter 2. The Quinazolinocarboline Alkaloids -- I. Introduction and Nomenclature -- II. Occurrence -- III. Structure and Synthesis -- IV. Biosynthesis -- V. Pharmacological Properties of Quinazolinocarboline Alkaloids and Synthetic Analogs -- References -- Chapter 3. Isoquinolinequinones from Actinomycetes and Sponges -- I. Introduction and Occurrence -- II. Saframycin-Type Antibiotics -- III. Renieramycin-Type Antibiotics -- IV. Naphthyridinomycin-Type Antibiotics -- V. Mimosamycin-Type Antibiotics -- VI. Biological Activity -- Addendum -- References -- Chapter 4. Camptothecin -- I. Introduction -- II. Total Synthesis -- III. Biogenesis -- IV. Medicinal Chemistry -- References -- Chapter 5. Amphibian Alkaloids -- I. Introduction -- II. Location and Function of Amphibious Venoms: Steroidal Alkaloids, Tetrodotoxin -- III. Spiropiperidines, cis-Decahydroquinolines, and Octahydroindolizidines -- IV. Neurotoxins, Receptors, and Ion Transport -- V. Epilogue. -- References -- Addendum -- Chapter 6. Simple Isoquinoline Alkaloids -- I. Introduction -- II. Simple Isoquinoline Alkaloids -- III. I-Phenyl-, 4-Phenyl-, and N-Benzyl-Substituted Simple Isoquinoline Alkaloids -- IV. Biogenesis -- V. Biological Effects -- References.
,
Chapter 7. Mammalian Alkaloids -- I. Introduction -- II. Chemical Considerations -- III. Analytical Separation and Detection of Mammalian Alkaloids -- IV. Production of 1,2,3,4-Tetrahydroisoquinolines inVitro -- V. Tetrahydroisoquinolines in Human and Animal Models -- VI. Mammalianβ-Carboline Formation -- VII. Alternative Modes of Mammalian Alkaloid Formation -- VIII. Metabolic Studies of Mammalian Alkaloids -- IX. Effects of Mammalian Alkaloids on Biochemical Processes -- X. Physiological and Behavioral Effects of Mammalian Alkaloids. -- XI. Summary -- References -- Index.
