Keywords:
Lectins.
;
Electronic books.
Description / Table of Contents:
Introduces Groundbreaking Approaches for Assessing Lectin Function Lectins and their ligands are under quite a heavy microscope due to their potential applications to pharmacology, immunology, cancer therapy, and agriculture. With growing interest in the glycobiology field, the body of research related to lectin roles has grown at an explosive rate, particularly in the past 20 years. Animal Lectins: A Functional View presents the most up-to-date analysis of these carbohydrate-binding, and potentially lifesaving, proteins in one comprehensive volume. This standard-setting resource presents new insights into the biological roles of most animal lectins, including their function in infection prevention through innate immunity. It also discusses such lectin behaviors as: Glycoprotein folding Sorting and targeting Cell adhesion Embryogenesis Cell-cell interactions and signaling Describes the Structural Basis of Protein-Carbohydrate Interactions Under the editorial guidance of two leading protein chemistry experts and with contributions from well-recognized field authorities, this book logically and systematically discusses both intracellular and extracellular lectin functions. It is an essential springboard for future field research and a clear and concise knowledge base that glycobiology, biochemistry, and immunology researchers cannot afford to be without.
Type of Medium:
Online Resource
Pages:
1 online resource (598 pages)
Edition:
1st ed.
ISBN:
9781420006971
URL:
https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=365520
DDC:
572/.69
Language:
English
Note:
Front cover -- Contents -- Foreword -- Preface -- Editors -- Contributors -- Part I: Introduction -- Chapter 1. Introduction to Animal Lectins -- Part II: Modern Approaches for Assessing Lectin Function -- Chapter 2. Structural Aspects of Lectin-Ligand Interactions -- Chapter 3. Thermodynamic Approaches to the Study of Affinity of Clustered Carbohydrate Epitopes in Galectin- Glycoconjugate Interactions -- Chapter 4. Deciphering Lectin Ligands through Glycan Arrays -- Chapter 5. Chromatography and Related Approaches for Qualitative and Quantitative Analyses of Lectin Specificity -- Chapter 6. Analysis of Whole-Genome and Other Data Resources to Characterize the Molecular, Structural, and Evolutionary Diversity of C-Type Lectins and Discover New Genes -- Chapter 7. Animal Models for Assessing the Biological Roles of Lectins -- Part III: Glycoprotein Folding, Sorting and Secretion, Targeting, Degradation, and Clearance -- Chapter 8. Calreticulin and Calnexin as Chaperones in Glycoprotein Folding -- Chapter 9. Role of L-Type Lectins in Glycoprotein Sorting and Trafficking -- Chapter 10. P-Type Lectins and Lysosomal Enzyme Targeting -- Chapter 11. M-Type Lectins as Novel Components of Secretory Pathways -- Chapter 12. Functional Aspects of the Hyaluronan and Chondroitin Sulfate Receptors -- Part IV: Cell Adhesion and Cell Surface Lattice Formation -- Chapter 13. Galectin-3 and Cancer -- Chapter 14. Myelin-Associated Glycoprotein (Siglec-4): A Nervous System Lectin That Regulates Axon-Myelin Stability and Axon Regeneration -- Chapter 15. Hyaluronan-Binding Proteoglycans -- Chapter 16. Roles of Coral Lectins in Morphological Change of Zooxanthellae -- Part V: Cell-Cell Interactions, Signaling, and Transport -- Chapter 17. Siglecs: Roles in Cell-Cell Interactions and Signaling -- Chapter 18. Signaling through the Fungal -Glucan Receptor Dectin-1.
,
Chapter 19. CD22: A Regulator of B Cell Survival and Signal Transduction -- Chapter 20. Galectins and Integrins in Pre-B Cell Development -- Chapter 21. Golgi N-Glycan Processing and Galectin Functions -- Part VI: Recognition and Effector Functions in Innate Immunity -- Chapter 22. Mannan-Binding Lectin Polymorphisms and Infectious Diseases -- Chapter 23. Immunoregulatory Roles of Lung Surfactant Proteins A and D -- Chapter 24. C-Type Lectin Receptors on Dendritic Cells -- Chapter 25. Structural and Functional Roles of C-Type Lectin Receptors on Natural Killer Cells -- Chapter 26. Activation of Lepidopteran Insect Innate Immune Responses by C-Type Immulectins -- Chapter 27. Galectins as Novel Regulators of Immune Cell Homeostasis and Inflammation -- Chapter 28. Interactions of Galectins with Leukocytes -- Chapter 29. Regulation of Immune Responses by Galectin-3 -- Chapter 30. X-Lectins: A New Family with Homology to the Homology to the Xenopus leavis Oocyte Lectin XL35 -- Chapter 31. F-Type Lectins: A New Family of Recognition Factors -- Chapter 32. Biology of FREPs: Diversified Lectins with Fibrinogen-Related Domains from the Freshwater Snail Biomphalaria glabrata -- Chapter 33. Lectins in Sand Fly-Leishmania Interactions -- Chapter 34. Ficolins: The Structural Basis for Recognition Plasticity -- Chapter 35. Hemolytic Lectin in Marine Invertebrates -- Chapter 36. Structure-Function Relationship in Mammalian Chitinase-Like Lectins -- Index -- Back cover.
