Keywords:
Electronic books.
Type of Medium:
Online Resource
Pages:
1 online resource (97 pages)
Edition:
1st ed.
ISBN:
9783318027327
Series Statement:
Else Kröner-Fresenius Symposia Series ; v.5
URL:
https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=3016650
DDC:
616.02/774
Language:
English
Note:
Cover -- Front Matter -- Contents -- Preface -- Adult Stem Cells in Aging, Diseases and Cancer -- The Else Kröner-Fresenius-Stiftung -- Introduction -- Speakers at the Symposium -- Steven Artandi, MD, PhD -- Axel Behrens, PhD -- Cédric Blanpain, MD, PhD -- Andrew Brack, PhD -- Anne Brunet, PhD -- Andrei V. Budanov, PhD -- Tao Cheng, MD -- Gerald de Haan, PhD -- Jan van Deursen, PhD -- Connie J. Eaves, PhD -- Bruce Edgar, PhD -- Hartmut Geiger, PhD -- Margaret A. Goodell, PhD -- Heinrich Jasper, PhD -- D. Leanne Jones, PhD -- Jan Karlseder, PhD -- Michael Milyavsky, PhD -- Huck-Hui Ng, PhD -- Andre Nussenzweig, PhD -- Emmanuelle Passegué, PhD -- Pier Giuseppe Pelicci, MD, PhD -- Thomas A. Rando, MD, PhD -- Hans-Reimer Rodewald, PhD -- Derrick Rossi, PhD -- Michael Rudnicki, PhD -- Karl Lenhard Rudolph, MD -- Björn Schumacher, PhD -- Manuel Serrano, PhD -- Toshio Suda, MD -- Elly M. Tanaka, PhD -- Andreas Trumpp, PhD -- Maarten van Lohuizen, PhD -- Amy J. Wagers, PhD -- Stem Cells in Adult Intestine -- Abstract -- Intestine -- Intestinal Stem Cells -- Stem Cells in Drosophila Midgut -- Notch and Delta -- Other Signaling Pathways -- Outlook -- References -- Molecular Mechanisms of Muscle Stem Cell Aging -- Abstract -- Morphological and Molecular Properties of Muscle Stem Cells -- Molecular Mechanism of Satellite Cell Aging -- Epigenetic Regulation of Myogenic Stem Cells during Aging -- Molecular Mechanism of Cardiac Muscle Aging and Disease -- Conclusions and Perspectives -- References -- Mechanism of Functional Alterations in Hematopoietic Stem Cell Aging -- Abstract -- Characteristics of Hematopoietic Stem Cells -- Functional Alteration of Hematopoietic Stem Cells during Aging -- Molecular Mechanisms in Hematopoietic Stem Cell Aging -- Epigenetic Regulation of Stem Cell Function -- DNA Damage Signaling in the Regulation of Hematopoietic Stem Cells.
,
Genes Controlling Quiescence and Self-Renewal of Hematopoietic Stem Cells -- Conclusions -- References -- The Microenvironment, Aging and Disease -- Abstract -- The Influence of the Niche and the Environment on Stem Cells in Disease and Aging -- Modeling Myelodysplastic Syndromes: The Role of the Niche -- Stem Cell Proliferation and Tissue Homeostasis in the Aging Drosophila Intestine -- Polarity and Wnt5 a Signaling Are Central to Stem Cell Aging -- References -- Sestrins in Aging and Metabolism -- Abstract -- Drosophila Sestrin as a Feedback Inhibitor of TOR Protects Drosophila from Accumulation of Aging-Related Pathologies -- Sesn2 and Sesn3 Maintain Metabolic Homeostasis in Mammalians -- References -- Telomeres and Stem Cell Aging -- Abstract -- Telomerase, Adult Stem Cells and Cancer -- Studying Telomerase in vivo -- Stalled Replication Induces the ALT Pathway -- Breast Stem Cells with High Telomerase Activity but Short Telomeres -- Pot1a Expression Enhances Colony Formation Ability of Hematopoietic Stem Cells -- Conclusions -- References -- DNA Damage and Checkpoint Responses in Adult Stem Cells -- Abstract -- DNA Damage Accumulation during Hematopoietic Stem Cell Aging -- p53-/p21-Dependent DNA Damage Response in Stem Cells -- DNA Damage Response in Human Hematopoietic Stem Cells -- Stem and Progenitor Cell Senescence in Aging -- Outlook -- References -- Thomas Hell Plays 'Vertigo' by György Ligeti -- Thomas Hell -- Author Index -- Subject Index -- Cover.
