Publication Date:
2017-02-25
Description:
IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting Nature Communications, Published online: 24 February 2017; doi:10.1038/ncomms14607 T cell mediated anti-tumour immune responses result in the emergence of an immune-resistant population in a process called immunoediting. Here, the authors show that immunoediting is associated with an increase in genomic rearrangements of tumour cells that requires both cytotoxic T cells and IFNγ exposure.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics