In:
Journal of the chemical society of pakistan, Chemical Society of Pakistan, Vol. 42, No. 1 ( 2020), p. 149-149
Abstract:
Three novel carboxylic arylhydrazone compounds named 2- oxo propionic acid terephthalal acyl dihydrazone (1), 2-ketoglutaric acid terephthalal acyl dihydrazone (2) and 2-ketoglutaric acid salicyl- hydrazone (3) were prepared and characterized by elemental analysis, IR and 1H NMR. The antibacterial activities of 1 and 2 against wheat rust and coliform were investigated. The results showed that 1 had more excellent antibacterial properties than 2 against both wheat rust and coliform. In addition, the title compounds interaction with calf-thymus DNA (CT-DNA) were measured by fluorescence spectra method which indicating that they combined with CT-DNA by groove binding through hydrogen bonds.
Type of Medium:
Online Resource
ISSN:
0253-5106
Uniform Title:
Synthesis, Characterization and Bioactivity of Three Carboxylic Arylhydrazone Compounds
Language:
Unknown
Publisher:
Chemical Society of Pakistan
Publication Date:
2020
detail.hit.zdb_id:
782712-X