In:
Key Engineering Materials, Trans Tech Publications, Ltd., Vol. 284-286 ( 2005-4), p. 957-960
Abstract:
The purpose of this study was to compare the bone regenerative effect of calcium
phosphate glass and glass-ceramics in the system of CaO-CaF2-P2O5-MgO-ZnO, which is already reported that promoted the bone-like tissue formation in vitro and formed new bone in Sprague-Dawley rats. We prepared calcium phosphate glass and glass-ceramics with Ca/P ratio of 0.6 using the system CaO-CaF2-P2O5-MgO-ZnO and subsequently milled to 400 µm. 4×4 mm 1-wall intrabony defects of six beagle dogs were surgically created and used in this study. 8 weeks after transplantation of the prepared calcium phosphate glass and glass-ceramics in the experimental group 1 and 2, respectively, the animals were sacrificed. No root resorption or ankylosis were observed in all groups. It can be examined that the prepared glass-ceramics were more effective in alveolar bone regeneration with statistical signigicant difference. In cementum regeneration, both the prepared glass
and glass-ceramics showed significantly different effect. However, there were no statistical significant difference neither in glass nor glass-ceramics in the amounts of junctional epithelium migration and connective tissue adhesion. Further study is required to control the flowability as well as reduce the absorption rate in vivo.
Type of Medium:
Online Resource
ISSN:
1662-9795
DOI:
10.4028/www.scientific.net/KEM.284-286
DOI:
10.4028/www.scientific.net/KEM.284-286.957
Language:
Unknown
Publisher:
Trans Tech Publications, Ltd.
Publication Date:
2005
detail.hit.zdb_id:
2073306-9
