In:
Molecules, MDPI AG, Vol. 19, No. 7 ( 2014-06-30), p. 9089-9100
Abstract:
A glucomannan-type polysaccharide, named BSP, was obtained from the tubers of Bletilla striata by ultrasonic-assisted extraction, ethanol precipitation, deproteination and gel-permeation chromatography. HPLC analysis revealed that BSP contained mannose and glucose in the molar ratio of 3.5:1. Its molecular weight (Mw) was estimated to be 20 kDa. Methylation analysis, FT-IR and NMR analyses indicated that BSP consisted of (1→4)-linked β-D-glucopyranosyl residues and (1→4)-linked β-D-mannopyranosyl residues. Cholesteryl succinate was linked to BSP to make it more amphiphilic and the degree of substitution of cholesteryl succinate-BSP was 3.2%. The critical micelle concentration of modified BSP was 0.001 mg/mL, suggesting it could self-assemble into nanoparticles in aqueous solution.
Type of Medium:
Online Resource
ISSN:
1420-3049
DOI:
10.3390/molecules19079089
Language:
English
Publisher:
MDPI AG
Publication Date:
2014
detail.hit.zdb_id:
2008644-1