In:
Biomolecules, MDPI AG, Vol. 10, No. 8 ( 2020-07-31), p. 1131-
Abstract:
A series of 2-arylbenzofurans and 2-arylbenzothiophenes was synthesized carrying three different side chains in position five. The synthesized compounds were tested for NF-κB inhibition to establish a structure activity relationship. It was found that both, the side chain in position five and the substitution pattern of the aryl moiety in position two have a significant influence on the inhibitory activity.
Type of Medium:
Online Resource
ISSN:
2218-273X
DOI:
10.3390/biom10081131
Language:
English
Publisher:
MDPI AG
Publication Date:
2020
detail.hit.zdb_id:
2701262-1