In:
Journal of the American Veterinary Medical Association, American Veterinary Medical Association (AVMA), Vol. 210, No. 5 ( 1997-03-01), p. 648-650
Abstract:
To determine whether it was possible to retrieve organisms, by means of bronchoalveolar lavage (BAL), from cats inoculated with Toxoplasma gondii . Design Experimental study. Animals 27 cats. Sixteen of the 27 were experimentally infected with feline immunodeficiency virus. Procedure All cats were inoculated with T gondii tachyzoites. Cats were grouped on the basis of feline immunodeficiency virus status and route (IV or intra-arterial) and number of tachyzoites administered. Bronchoalveolar lavage was performed by means of a standard technique. Lavage fluid was evaluated cytologically for tachyzoites. Results Clinical signs of toxoplasmosis varied widely among individual cats, but were generally most pronounced in group-1 and -2 cats (n = 5 each) and less pronounced in group-3 (n = 5) cats. Group-4 and -5 cats (n = 6 each) did not have clinical signs of toxoplasmosis. In 14 of the 15 cats in groups 1, 2, and 3, tachyzoites were detected in BAL flu id collected 7 days after inoculation. Tachyzoites were detected 14 days after inoculation in the single cat without tachyzoites 7 days after inoculation. A necropsy was performed on 9 of these cats, and tachyzoites were identified histologically in 4 of the 9. Tachyzoites were not detected in BAL fluid collected 3 days (n = 6) or 7 days (n = 6) after inoculation from the 12 cats in groups 4 and 5. Tachyzoites were not identified histologically in any of these 12 cats. Clinical Implications BAL may be useful in the diagnosis of toxoplasmosis. Particularly in cats with signs of pulmonary involvement. ( J Am Vet Med Assoc 1997;210:648–650
Type of Medium:
Online Resource
ISSN:
0003-1488
DOI:
10.2460/javma.1997.210.05.648
Language:
Unknown
Publisher:
American Veterinary Medical Association (AVMA)
Publication Date:
1997
detail.hit.zdb_id:
390811-2
SSG:
22
