In:
Genetics, Oxford University Press (OUP), Vol. 177, No. 3 ( 2007-11-01), p. 1963-1966
Abstract:
In the case of selective genotyping, the usual permutation test to establish statistical significance for quantitative trait locus (QTL) mapping can give inappropriate significance thresholds, especially when the phenotype distribution is skewed. A stratified permutation test should be used, with phenotypes shuffled separately within the genotyped and ungenotyped individuals.
Type of Medium:
Online Resource
ISSN:
1943-2631
DOI:
10.1534/genetics.107.080093
Language:
English
Publisher:
Oxford University Press (OUP)
Publication Date:
2007
detail.hit.zdb_id:
1477228-0
SSG:
12