In:
JCEM Case Reports, The Endocrine Society, Vol. 2, No. 2 ( 2024-01-08)
Abstract:
A case of recurrent insulinoma spanning 4 decades is described. Following a delayed diagnosis, hyperinsulinemic hypoglycemia was confirmed in a 24-year-old woman during early pregnancy. Initial surgery, culminating in subtotal pancreatectomy, was noncurative. A 1-cm insulinoma was subsequently resected from the head of the pancreas postpartum, with postoperative resolution of hypoglycemia. However, 32 years later, the patient experienced a recurrence of hypoglycemic symptoms. Eventually, a subcentimeter extrapancreatic lesion was identified anterior to the pancreatic head on gallium-68 DOTA-Exendin-4 positron emission tomography/computed tomography. In 2022, a third operation was performed, with excision of a 4 × 3 mm tumor adjacent to the pancreatic head, and histology confirming insulinoma. She was again cured of symptoms.
Type of Medium:
Online Resource
ISSN:
2755-1520
DOI:
10.1210/jcemcr/luad168
Language:
English
Publisher:
The Endocrine Society
Publication Date:
2024
detail.hit.zdb_id:
3166308-4
