In:
United European Gastroenterology Journal, Wiley, Vol. 9, No. 3 ( 2021-04), p. 388-397
Abstract:
Alpha‐fetoprotein (AFP) is the most commonly used biomarker for hepatocellular carcinomas (HCCs), but accuracy of static and dynamic AFP values is limited and the prognostic significance is under debate. High static and dynamic AFP variables prior to therapy are associated with reduced survival rates of HCC patients across different tumour stages and treatment modalities. In patients with more favourable prognosis, AFP‐slope prior to therapy was a better predictor for overall survival in comparison with static AFP values. Addition of AFP‐slope to established prognostic parameters might improve prognostic classification for a subgroup of HCC.
Type of Medium:
Online Resource
ISSN:
2050-6406
,
2050-6414
DOI:
10.1177/2050640620972611
Language:
English
Publisher:
Wiley
Publication Date:
2021
detail.hit.zdb_id:
2728585-6