In:
Circulation Research, Ovid Technologies (Wolters Kluwer Health), Vol. 4, No. 6 ( 1956-11), p. 727-730
Abstract:
The possibility that nitroglyoerin modifies the metabolic effects of the sympathomimetic amines was tested in cats. Changes in the heart rate, blood pressure, height of the electrocardiographic T-wave and myocardial oxygen consumption following the injection of epinephrine or l-arterenol were compared with changes in these indices after nitroglycerin was given with these sympathomimetic amines. The conclusion is reached that nitroglycerin does not significantly influence the effects of epinephrine or l-arterenol on the heart rate, the height of the electrocardiographic T-wave or myocardial oxygen consumption. There is no evidence in these experiments to support the concept that nitroglycerin metabolically neutralizes the myocardial anoxating properties of the sympathomimetic amines.
Type of Medium:
Online Resource
ISSN:
0009-7330
,
1524-4571
DOI:
10.1161/01.RES.4.6.727
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
1956
detail.hit.zdb_id:
1467838-X
