In:
European Neurology, S. Karger AG, Vol. 65, No. 2 ( 2011), p. 94-98
Abstract:
〈 i 〉 Background: 〈 /i 〉 Pyrexia is often associated with unfavorable stroke outcomes. However, limited information is available on the relationship between the causes of poststroke hyperthermia and stroke prognosis, especially for mild-to-moderate neurogenic pyrexia in acute cerebral infarction. 〈 i 〉 Aims: 〈 /i 〉 To compare the differences in the clinical features and characteristics of pyrexia as well as its prognosis among acute cerebral infarction patients with mild-to-moderate neurogenic pyrexia, with infectious pyrexia, and without pyrexia. The focus was on mild-to-moderate neurogenic pyrexia. 〈 i 〉 Methods: 〈 /i 〉 A total of 709 patients with acute cerebral infarction were prospectively recruited and their clinical data were analyzed. 〈 i 〉 Results: 〈 /i 〉 No significant difference was detected in age, gender, history of smoking, hypertension, or diabetes among the 3 groups (p 〉 0.05). Patients with mild-to-moderate neurogenic pyrexia and those with infectious pyrexia had higher baseline National Institutes of Health Stroke Scale (NIHSS) scores (15.1 ± 6.7, p = 0.003; 14.3 ± 8.1, p = 0.002, respectively), lower 3-month Barthel index (BI) values (64.2 ± 40.7, p 〈 0.001; 61.9 ± 49.3, p 〈 0.001, respectively) and higher 3-month mortality rates (13%, p = 0.026; 16%, p 〈 0.001, respectively) than patients without pyrexia (NIHSS score 11.4 ± 7.9; BI 82.6 ± 39.8, and mortality rate 6%, respectively). No difference existed in these parameters between the 2 pyrexia groups (p 〉 0.05), but mild-to-moderate neurogenic pyrexia had an earlier onset and a shorter duration than infectious pyrexia (p 〈 0.001). 〈 i 〉 Conclusions: 〈 /i 〉 Acute cerebral infarction patients with mild-to-moderate neurogenic pyrexia had a similar prognosis compared to those with infectious pyrexia. Mild-to-moderate neurogenic pyrexia is possibly associated with stroke severity.
Type of Medium:
Online Resource
ISSN:
0014-3022
,
1421-9913
Language:
English
Publisher:
S. Karger AG
Publication Date:
2011
detail.hit.zdb_id:
1482237-4
