In:
Journal of Innovative Optical Health Sciences, World Scientific Pub Co Pte Ltd, Vol. 10, No. 01 ( 2017-01), p. 1650032-
Abstract:
We propose a novel optical method for glucose measurement based on diffuse photon-pair density wave (DPPDW) in a multiple scattering medium (MSM) where the light scattering of photon-pair is induced by refractive index mismatch between scatters and phantom solution. Experimentally, the DPPDW propagates in MSM via a two-frequency laser (TFL) beam wherein highly correlated pairs of linear polarized photons are generated. The reduced scattering coefficient [Formula: see text] and absorption coefficient [Formula: see text] of DPPDW are measured simultaneously in terms of the amplitude and phase measurements of the detected heterodyne signal under arrangement at different distances between the source and detection fibers in MSM. The results show that the sensitivity of glucose detection via glucose-induced change of reduced scattering coefficient ([Formula: see text]) is 0.049%[Formula: see text] mM[Formula: see text] in a 1% intralipid solution. In addition, the linear range of [Formula: see text] vs glucose concentration implies that this DPPDW method can be used to monitor glucose concentration continuously and noninvasively subcutaneously.
Type of Medium:
Online Resource
ISSN:
1793-5458
,
1793-7205
DOI:
10.1142/S1793545816500322
Language:
English
Publisher:
World Scientific Pub Co Pte Ltd
Publication Date:
2017
detail.hit.zdb_id:
2515441-2
