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    MODELING YEAST OSMOADAPTATION AT DIFFERENT LEVELS OF RESOLUTION
    World Scientific Pub Co Pte Ltd ; 2013
    In:  Journal of Bioinformatics and Computational Biology Vol. 11, No. 02 ( 2013-04), p. 1330001-
    Details
    In: Journal of Bioinformatics and Computational Biology, World Scientific Pub Co Pte Ltd, Vol. 11, No. 02 ( 2013-04), p. 1330001-
    Abstract: We review the proposed mathematical models of the response to osmotic stress in yeast. These models mainly differ in the choice of mathematical representation (e.g. Bayesian networks, ordinary differential equations, or rule-based models), the extent to which the modeling is data-driven, and predictability. The overview exemplifies how one biological system can be modeled with various modeling techniques and at different levels of resolution, and how the choice typically is based on the amount and quality of available data, prior information of the system, and the research question in focus. As a natural part of the overview, we discuss requirements, advantages, and limitations of the different modeling approaches.
    Type of Medium: Online Resource
    ISSN: 0219-7200 , 1757-6334
    URL: Article
    DOI: 10.1142/S0219720013300013
    Language: English
    Publisher: World Scientific Pub Co Pte Ltd
    Publication Date: 2013
    SSG: 12
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