In:
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, Vol. 52, No. 3 ( 2008-03), p. 1144-1146
Abstract:
Incomplete killing was observed for caspofungin against Candida glabrata , which was associated with increased SLT2 expression and elevated chitin content. In contrast, fungicidal activity and no chitin increase were observed in an isogenic Δ slt2 strain, suggesting a role for SLT2 and chitin production in the response of C. glabrata to caspofungin.
Type of Medium:
Online Resource
ISSN:
0066-4804
,
1098-6596
DOI:
10.1128/AAC.01542-07
Language:
English
Publisher:
American Society for Microbiology
Publication Date:
2008
detail.hit.zdb_id:
1496156-8
SSG:
12
SSG:
15,3