In:
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, Vol. 60, No. 8 ( 2016-08), p. 5014-5017
Abstract:
We report the complete nucleotide sequence of a plasmid, pA31-12, carrying bla CTX-M-55 and mcr-1 from a chicken Escherichia coli isolate. pA31-12 has an IncI2 replicon that displays extensive sequence similarity with pHN1122-1-borne bla CTX-M-55 and pHNSHP45-borne mcr-1 . Insertion sequences IS Ecp1 and IS Apl1 are responsible for the mobilization of bla CTX-M-55 and mcr-1 , respectively. The colocalization of mcr-1 with an extended-spectrum β-lactamase gene on a conjugative plasmid may accelerate the dissemination of both genes by coselection.
Type of Medium:
Online Resource
ISSN:
0066-4804
,
1098-6596
DOI:
10.1128/AAC.00774-16
Language:
English
Publisher:
American Society for Microbiology
Publication Date:
2016
detail.hit.zdb_id:
1496156-8
SSG:
12
SSG:
15,3