In:
Science, American Association for the Advancement of Science (AAAS), Vol. 251, No. 4992 ( 1991-01-25), p. 437-439
Abstract:
CP-96,345, a nonpeptide substance P antagonist, is selective for the tachykinin NK1 receptor. The compound binds to a single population of sites in guinea pig brain and potently inhibits substance P-induced excitation of locus ceruleus neurons. CP-96,345 should be a useful tool for studying the action of substance P in the central nervous system.
Type of Medium:
Online Resource
ISSN:
0036-8075
,
1095-9203
DOI:
10.1126/science.1703324
Language:
English
Publisher:
American Association for the Advancement of Science (AAAS)
Publication Date:
1991
detail.hit.zdb_id:
128410-1
detail.hit.zdb_id:
2066996-3
SSG:
11