In:
Veterinary Clinical Pathology, Wiley, Vol. 52, No. 1 ( 2023-03), p. 97-101
Abstract:
A 9‐week‐old puppy with refractory seizures and a dome‐shaped head presented to the Mississippi State College of Veterinary Medicine Specialty Center for suspected hydrocephalus. Computerized tomography (CT) findings included transtentorial herniation and an intra‐axial mass with dystrophic mineralization. Cerebrospinal fluid analysis revealed an increased nucleated cell count of 1100/μl (RI 〈 5/μl), erythrocyte count of 2.2 × 10 6 /μl, and markedly increased microprotein of 1939 mg/dl (RI 〈 30 mg/dl). On cytologic examination of the CSF, numerous erythrophagocytic, and hemosiderin‐laden macrophages were observed, which indicated chronic active hemorrhage. Many neutrophils, macrophages, and lymphocytes that contained numerous intracytoplasmic, pleomorphic, bright yellow crystals were observed. Considering the ongoing hemorrhage, the crystals were presumed to be hematoidin. A biopsy with histopathology was performed on the intra‐axial mass, and the results were consistent with a vascular hamartoma. We speculate that the formation of these crystals was related to the ongoing hemorrhage associated with the vascular hamartoma. Identification of these crystals may be useful to aid in the identification of chronic hemorrhage associated with vascular malformations or lesions within the central nervous system.
Type of Medium:
Online Resource
ISSN:
0275-6382
,
1939-165X
Language:
English
Publisher:
Wiley
Publication Date:
2023
detail.hit.zdb_id:
2114702-4
SSG:
22
