In:
Pediatric Transplantation, Wiley, Vol. 26, No. 2 ( 2022-03)
Abstract:
A paucity of research regarding the psychosocial outcomes after TPIAT exists. Methods Adults ( 〉 18 years), adolescents (13–18 years), and children (5–12 years) with their parents were administered questionnaires at the time of evaluation for TPIAT and 1‐year postsurgery to assess psychosocial outcomes. Results A total of 13 adults (6 male, 46%; mean age 35.2 years) and 9 children/adolescents (4 female, 44.4%; mean age 11.78 years) with CP were included in the study. A total of 69.2% of the adults and 66.7% of the children and adolescents were insulin dependent at 1‐year postsurgery. In adults, improvements on the SF‐36 pain ( p = .001) and general health ( p = .045) subscales were generally observed 1‐year postsurgery. Adult patients who underwent robotic‐assisted surgery compared to open surgery specifically reported better general health on the SF‐36 ( p 〈 .05) at 1 year. For children and adolescents, reductions in average pain in the last week ( p 〈 .05), pain interference ( p 〈 .001), and fatigue were observed ( p 〈 .05) at 1‐year postsurgery. For the entire sample, using repeated measures ANOVA and covarying for age, significant differences were found 1‐year postsurgery in average pain in the last week ( p = .034) and pain interference with the following categories: general activity ( p 〈 .001), walking ( p = .04), normal work ( p = .003), sleep ( p = .002), and enjoyment in life ( p = .007). Conclusions While few transplant centers offer this treatment, the improvement in quality of life suggests this may be a viable treatment option for those with CP complicated by intractable pain. (IRB Approval PRO 19080302).
Type of Medium:
Online Resource
ISSN:
1397-3142
,
1399-3046
Language:
English
Publisher:
Wiley
Publication Date:
2022
detail.hit.zdb_id:
1390284-2
detail.hit.zdb_id:
2008614-3
