In:
Pediatrics International, Wiley, Vol. 57, No. 1 ( 2015-02), p. 169-171
Abstract:
A 5‐year‐old boy with glioblastoma relapsed soon after postoperative irradiation in combination with temozolomide. Second‐line chemotherapy was also ineffective; therefore, the bevacizumab and irinotecan were given after a third gross‐total resection of the tumor. Treatment was interrupted for 1 month due to development of posterior reversible encephalopathy syndrome, but was re‐initiated at a lower dose of bevacizumab with prolonged intervals between treatments. The patient was alive and disease free 2 years after initial diagnosis. Bevacizumab and irinotecan are a promising regimen for pediatric cases of recurrent glioblastoma after gross‐total resection, although the optimal treatment schedule must be determined on a patient‐by‐patient basis.
Type of Medium:
Online Resource
ISSN:
1328-8067
,
1442-200X
DOI:
10.1111/ped.2015.57.issue-1
Language:
English
Publisher:
Wiley
Publication Date:
2015
detail.hit.zdb_id:
2008621-0
detail.hit.zdb_id:
1470376-2