In:
Journal of Applied Microbiology, Oxford University Press (OUP)
Abstract:
We aimed to investigate the prevalence, pathology, and characterization of S. dysgalactiae subsp. equisimilis (SDSE) in slaughtered pigs of India. Methods and results We collected 1254 morbid tissues (lungs-627, spleen-627) and 627 heart-blood from 627 slaughtered pigs. The bacterial isolation, antibiogram, virulence gene profiling, and mouse pathogenicity testing were performed for the detection and characterization of SDSE. A total of 177 isolates (heart-blood-160; tissues-17) were recovered from 627 slaughtered pigs with higher isolation rate in heart-blood (25.51%). The prevalence of SDSE was 11% in morbid tissues by PCR. Majority of isolates showed higher detection of Streptolysin O, followed by streptokinase and extracellular phospholipase A virulence genes with higher degree of resistance to azithromycin, clindamycin, erythromycin, and penicillin antibiotics. Mouse pathogenicity testing confirmed virulence based on histopathological lesions and re-isolation of SDSE. Conclusions Our findings highlight the high prevalence of SDSE in slaughtered pigs. The presence of virulence genes and mouse pathogenicity testing confirm their pathogenic potential.
Type of Medium:
Online Resource
ISSN:
1365-2672
DOI:
10.1093/jambio/lxae002
Language:
English
Publisher:
Oxford University Press (OUP)
Publication Date:
2024
detail.hit.zdb_id:
2020421-8