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    DSigDB: drug signatures database for gene set analysis
    Oxford University Press (OUP) ; 2015
    In:  Bioinformatics Vol. 31, No. 18 ( 2015-09-15), p. 3069-3071
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    In: Bioinformatics, Oxford University Press (OUP), Vol. 31, No. 18 ( 2015-09-15), p. 3069-3071
    Abstract: Summary: We report the creation of Drug Signatures Database (DSigDB), a new gene set resource that relates drugs/compounds and their target genes, for gene set enrichment analysis (GSEA). DSigDB currently holds 22 527 gene sets, consists of 17 389 unique compounds covering 19 531 genes. We also developed an online DSigDB resource that allows users to search, view and download drugs/compounds and gene sets. DSigDB gene sets provide seamless integration to GSEA software for linking gene expressions with drugs/compounds for drug repurposing and translational research. Availability and implementation: DSigDB is freely available for non-commercial use at http://tanlab.ucdenver.edu/DSigDB. Supplementary information:  Supplementary data are available at Bioinformatics online. Contact:  aikchoon.tan@ucdenver.edu
    Type of Medium: Online Resource
    ISSN: 1367-4811 , 1367-4803
    URL: Article
    DOI: 10.1093/bioinformatics/btv313
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2015
    detail.hit.zdb_id: 1468345-3
    SSG: 12
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