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    Determination by UPLC-MS of four dammarane-type saponins from heat-processed Gynostemma pentaphyllum
    Informa UK Limited ; 2014
    In:  Bioscience, Biotechnology, and Biochemistry Vol. 78, No. 2 ( 2014-02-01), p. 311-316
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    In: Bioscience, Biotechnology, and Biochemistry, Informa UK Limited, Vol. 78, No. 2 ( 2014-02-01), p. 311-316
    Abstract: Heat-processed Gynostemma pentaphyllum and its main dammaran-type saponins, gypenoside L, gypenoside LI, damulin B, and damulin A, possess non-small cell lung carcinoma A549 cell inhibitory activity. We established in this study a method by ultra-high performance liquid chromatography with tandem mass spectrometry for determination of the saponins and also investigated their content change in heat-processed G. pentaphyllum. The main saponins increased with increasing heating temperature and time. Further investigation showed that they were produced from gypenoside XLVI and gypenoside LVI by undergoing hydrolysis during the heat treatment.
    Type of Medium: Online Resource
    ISSN: 0916-8451 , 1347-6947
    URL: Article
    DOI: 10.1080/09168451.2014.882751
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2014
    detail.hit.zdb_id: 2110940-0
    SSG: 12
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