In:
Proceedings of the National Academy of Sciences, Proceedings of the National Academy of Sciences, Vol. 73, No. 9 ( 1976-09), p. 3220-3223
Abstract:
The mechanism of nuclear DNA replication in radicles of germinating cotton ( Gossypium barbadense ) was investigated. Pulse-labeling with [ 3 H]thymidine indicates that replication intermediates are of small molecular weight (4-10S) and behave as if single-stranded. Prolonged labeling indicates that intermediates are of discrete size, suggesting a mechanism of discontinuous replication. Electron microscopy of nuclear DNA demonstrates a complex architecture which may include “eye forms” and “forks” similar to those reported in prokaryotes and animal systems. The possible universality of DNA replication mechanisms is discussed.
Type of Medium:
Online Resource
ISSN:
0027-8424
,
1091-6490
DOI:
10.1073/pnas.73.9.3220
Language:
English
Publisher:
Proceedings of the National Academy of Sciences
Publication Date:
1976
detail.hit.zdb_id:
209104-5
detail.hit.zdb_id:
1461794-8
SSG:
11
SSG:
12
