In:
Artificial Organs, Wiley, Vol. 22, No. 6 ( 1998-06), p. 488-492
Abstract:
A bypass flow rate estimation and control system (BECS) for an implantable centrifugal blood pump (ICBP) has been developed in our institute. The estimated flow rate (EF) of the ICBP was derived from the electric power consumption, the rotating speed of a motor, and the blood viscosity presumed by the hematocrit and body temperature. The error in the EF was 0.5 ± 0.4 L/min in in vivo experiments for 40 days. The rotating speed of the motor was controlled automatically every 200 ms to bring the EF in accord with the desired flow rate (DF). The reactivity and accuracy of the BECS were investigated in in vitro and in vivo experiments. The ICBP was operated by the BECS in a mock circuit in parallel with a pulsatile ventricular assist device (PVAD) to simulate left heart bypass. The reactivity was evaluated by changing the DF from 7 L/min to 5 L/min at an afterload of 160/97 mm Hg. To evaluate the accuracy of the BECS, the ICBP was driven under the aortic pressure of 110/85 mm Hg in the abdominal wall of an adult goat (70 kg). The DF was set at 5 L/min for 4 min for the goat in an awake condition. It took 13 s to change the flow rate in the in vitro experiment. The measured flow rate (MF) was maintained at 5.0 ± 0.2 L/min by the BECS in vivo. In conclusion, the BECS has moderate reactivity and accuracy.
Type of Medium:
Online Resource
ISSN:
0160-564X
,
1525-1594
DOI:
10.1046/j.1525-1594.1998.06130.x
Language:
English
Publisher:
Wiley
Publication Date:
1998
detail.hit.zdb_id:
2003825-2
