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    In: Ultrasound in Obstetrics & Gynecology, Wiley, Vol. 18, No. s1 ( 2001-10)
    Abstract: A prospective cross‐sectional study was developed in order to determine reference ranges for the umbilical cord cross‐sectional area (UCCSA) during normal pregnancies (patients with known dates of LMP and an ultrasound examination before the 20th week, without any pathologic condition). The measurements of the UCCSA were obtained in a plane adjacent to the insertion of the cord abdomen, as proposed by Raio et al , 1999. The inclusion criteria were: (1) singleton pregnancy, (2) gestation age 〉 20 weeks, (3) intact membranes, (4) normal umbilical Doppler flow velocimetry. The exclusion criteria, in the presence of any of those, were: (1) congenital and/or chromosomal abnormalities; (2) pregnancy complications (any type); (3) inadequate size for gestational age when the examination was performed, i.e. the weight below the 10th percentile or above the 90th; (4) abnormal AFI for the gestational age. The patients were examined and included only once. During the period of the study (February 2000–May 2001), 545 patients were examined, after meeting the inclusion criteria determined for the present study. The age of the patients ranged from 15 to 42 years (mean = 26.7 ± 4.8), 242 patients (44.4%) had two gestations, 135 patients (28.1%) were at their first gestation, 129 patients (23.7%) were at their third gestation and 39 patients had four or more gestations (3.8%). The ultrasound machine used was the Synergy Multi Sync M 500 and the statistical analysis was performed by the program called Statistical Package for Social Sciences (SPSS). Our data were considered normally by the Kolmogorov–Smirnov test and then we figured the nomogram by linear regression analysis. The analysis of variance obtained through the F ‐test (value = 356.27) showed that our regression model was significant at the level of P   〈  0.001, showing that the curve represented well the studied population and that the confidence interval (95%) contained the real value of the UCCSA. The regression equation was: y  = − 532.27 + 44.358 x  − 0.6555 x 2 . We conclude that, there is a progressive increase in the UCCSA up to the 32nd week of gestation, followed by a stabilization until the 34th week and a fall of the values from the 35th week of gestation.
    Type of Medium: Online Resource
    ISSN: 0960-7692 , 1469-0705
    Language: English
    Publisher: Wiley
    Publication Date: 2001
    detail.hit.zdb_id: 2020512-0
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