In:
International Journal of Gynecology & Obstetrics, Wiley, Vol. 113, No. 3 ( 2011-06), p. 178-182
Abstract:
To evaluate the effectiveness/safety of systemic methotrexate (MTX) treatment versus transcatheter arterial chemoembolization using different embolic agents for termination of cesarean scar pregnancy (CSP). Methods Women with CSP were randomized to receive intravenous infusion of MTX (group 1, n = 13), or chemoembolization with MTX and either gelatin sponge (GS; group 2, n = 15) or polyvinyl alcohol (PVA; group 3, n = 16) particles. Uterine suction curettage followed all procedures. Bleeding volume, time until resolution of serum β‐hCG, and length of hospital stay were recorded as outcome endpoints. Results Bleeding volume was smaller in groups 2 (mean ± SD, 73 ± 20 mL) and 3 (63 ± 22 mL) than in group 1 (952 ± 471 mL) ( P 〈 0.001). Time until resolution of β‐hCG was shorter in groups 2 (29 ± 16 days) and 3 (30 ± 19 days) than in group 1 (57 ± 25 days) ( P 〈 0.01). Length of hospital stay was shorter in groups 2 (13 ± 4 days) and 3 (12 ± 3 days) than in group 1 (36 ± 8 days) ( P 〈 0.01). Conclusion Transcatheter arterial chemoembolization was more effective than systemic MTX treatment for termination of CSP. Large cohort studies are warranted to compare effectiveness between PVA and GS particles.
Type of Medium:
Online Resource
ISSN:
0020-7292
,
1879-3479
DOI:
10.1016/j.ijgo.2010.11.027
Language:
English
Publisher:
Wiley
Publication Date:
2011
detail.hit.zdb_id:
1500480-6
