In:
Phytotherapy Research, Wiley, Vol. 32, No. 1 ( 2018-01), p. 94-102
Abstract:
The purpose was to examine cardiovascular responses to supplementation with p ‐synephrine alone and in combination with caffeine during quiet sitting. Sixteen subjects were given (in double‐blind manner) either 103 mg of p‐ synephrine (S), 233 mg of caffeine +104 mg of p ‐synephrine (LC + S), 240 mg of caffeine (LC), 337 mg of caffeine +46 mg of p ‐synephrine (HC + S), 325 mg of caffeine (HC), or a placebo. The subjects sat quietly for 3 hr while heart rate (HR) and blood pressure were measured. Only HC + S and HC significantly increased mean systolic blood pressure (SBP) during the second hour and tended to increase mean SBP during the third hour. Mean diastolic blood pressure in S was significantly lower than the other trials during the first and second hours, and mean arterial pressure was significantly lower in S compared to the LC, LC + S, HC, and HC + S trials. No differences were observed in HR. Consumption of p ‐synephrine may acutely reduce diastolic blood pressure and mean arterial pressure and not affect SBP or HR during quiet sitting. The addition of p ‐synephrine to caffeine did not augment SBP or HR indicating that consumption of up to 104 mg of p ‐synephrine does not induce cardiovascular stress during quiet sitting.
Type of Medium:
Online Resource
ISSN:
0951-418X
,
1099-1573
Language:
English
Publisher:
Wiley
Publication Date:
2018
detail.hit.zdb_id:
1493490-5
detail.hit.zdb_id:
639136-9
SSG:
15,3