In:
Journal of Peptide Science, Wiley, Vol. 7, No. 5 ( 2001-05), p. 227-249
Abstract:
Amyloid formation plays a central role in the cause and progression of Alzheimer's disease. The major component of this amyloid is the amyloid‐β (Aβ) peptide, which is currently the subject of intense study. This review discusses some recent studies in the area of Aβ synthesis, purification and structural analysis. Also discussed are proposed mechanisms for Aβ‐induced neurotoxicity and some recent advances in the development of Aβ‐related therapeutic strategies. Copyright © 2001 European Peptide Society and John Wiley & Sons, Ltd.
Type of Medium:
Online Resource
ISSN:
1075-2617
,
1099-1387
Language:
English
Publisher:
Wiley
Publication Date:
2001
detail.hit.zdb_id:
1491819-5
SSG:
12