In:
Psycho-Oncology, Wiley, Vol. 31, No. 6 ( 2022-06), p. 995-1002
Abstract:
Screening glioma patients regularly for possible mood disorders may facilitate early identification and referral of patients at risk. This study evaluated if the EORTC QLQ‐C30 Emotional Functioning (EF) scale could be used as an initial screening measure to identify patients possibly having a mood disorder. Methods EORTC QLQ‐C30 EF and Hospital Anxiety and Depression Scale (HADS) scores were collected as part of a study assessing the impact of timing of patient‐reported outcome assessments on actual health‐related quality of life outcomes ( N = 99). Spearman correlations and Mann‐Whitney U tests were used to determine the association between the EF and HADS (sub)scales. Receiver Operating Characteristic analyses were performed to determine optimal cut‐off EF scores to identify patients possibly having a mood disorder (i.e. HADS subscale score ≥8 points). Results EF and HADS (sub)scales correlated moderately (HADS‐A: r = −0.65; HADS‐D: r = −0.52). Significant EF score differences were found between patients with HADS ≥8 versus 〈 8 points (HADS‐A: mean difference (MD) = 32 and HADS‐D: MD = 23). The EF scale had excellent (HADS‐A; AUC = 0.88) and borderline excellent (HADS‐D; AUC = 0.78) distinguishing capabilities. A statistically optimal (EF score 〈 80) and a most inclusive (sensitivity of 100%, corresponding to an EF score 〈 97) EF cut‐off score correctly identified 88.0% and 96.0% of patients with a possible mood disorder, respectively. Conclusion EORTC QLQ‐C30 EF scale seems to be an appropriate screening measure to identify glioma patients possibly having a mood disorder in need of further assessment.
Type of Medium:
Online Resource
ISSN:
1057-9249
,
1099-1611
Language:
English
Publisher:
Wiley
Publication Date:
2022
detail.hit.zdb_id:
1495115-0
SSG:
5,2
