In:
Journal of Clinical Laboratory Analysis, Wiley, Vol. 30, No. 3 ( 2016-05), p. 254-257
Abstract:
Assays based on multiplex immunoassay (MIA) technology have demonstrated advantages over enzyme‐linked immunosorbent assay (ELISA) and radioimmunoassay (RIA). Its acceptance depends on how well it performs in comparison to older techniques. The aim is to compare the results of leptin using RIA versus MIA. Methods We analyzed 81 samples of umbilical cord blood of healthy term newborns by RIA and MIA. Results The concordance correlation coefficient was 0.158 (95% CI 0.10–0.21). Pearson's correlation coefficient was 0.6651 (95% CI 0.52–0.77; P 〈 0.0001). In the Bland–Altman plot, concordance is acceptable because most of the measurements are within a mean of ±1.96 SD. Conclusions As shown by the Bland–Altman plot, there is concordance by both methods, but with a weak correlation.
Type of Medium:
Online Resource
ISSN:
0887-8013
,
1098-2825
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
2001635-9