In:
SID Symposium Digest of Technical Papers, Wiley, Vol. 45, No. 1 ( 2014-06), p. 42-45
Abstract:
In this study, we presented a pilot study of metronomic photodynamic therapy (mPDT) by the use of organic light emitting diode (OLED) in treating treatment of brain tumor. The low cost, lightweight, and low fluence rate OLED has significant potential in the clinical mPDT applications. In this study, we treated nude mice with glioblastma by 5‐aminolevulinic acid (ALA) mediated OLED, mPDT. Afterwards, we investigated the tumor severity though bioluminescenct imaging and recorded survival days. Compared to control group (ALA treatment without illumination), PDT group mice showed increased survival days. This pilot study suggests that OLED is a useful light source for mPDT.
Type of Medium:
Online Resource
ISSN:
0097-966X
,
2168-0159
DOI:
10.1002/sdtp.2014.45.issue-1
DOI:
10.1002/j.2168-0159.2014.tb00012.x
Language:
English
Publisher:
Wiley
Publication Date:
2014
detail.hit.zdb_id:
2526337-7