In:
European Journal of Immunology, Wiley, Vol. 23, No. 10 ( 1993-10), p. 2711-2713
Abstract:
The early activation antigen CD69 is a member of a supergene family of type II integral membrane proteins with a C‐type lectin domain. In recent reports the genes encoding the natural killer (NK) cell‐related molecules of this supergene family, NKR‐P1, NK1.1 and Ly‐49, were shown to be clustered in a chromosomal region in mouse, termed the NK gene complex. The human homologue of this complex is likely to reside on chromosome 12 near the PRP locus (12p13.2). By analyzing T cell hybrids, the CD69 gene was previously mapped to human chromosome 12. Here we report the regional sublocalization of the human CD69 gene to chromosome bands 12p12.3‐p13.2, suggesting that CD69 belongs to one linkage group together with different cell surface molecules on NK cells.
Type of Medium:
Online Resource
ISSN:
0014-2980
,
1521-4141
DOI:
10.1002/eji.1830231051
Language:
English
Publisher:
Wiley
Publication Date:
1993
detail.hit.zdb_id:
1491907-2