In:
Developmental Dynamics, Wiley, Vol. 247, No. 1 ( 2018-01), p. 250-261
Abstract:
The new Cre‐expressing mouse line (Six1‐21‐NLSCre) was established. The Cre line induced genetic recombination in the progenitor domain for otic/epibranchial placodes, olfactory epithelium and Rathke's pouch. The recombination pattern was similar yet distinct from Pax2‐Cre/Pax8‐Cre lines. The results suggested that the continuous but complex expression pattern of Six1 during sensory organ formation is pieced together by separate enhancers. The Cre line should be useful to understand sensory development.
Type of Medium:
Online Resource
ISSN:
1058-8388
,
1097-0177
Language:
English
Publisher:
Wiley
Publication Date:
2018
detail.hit.zdb_id:
1473797-8
SSG:
12