In:
Drug Testing and Analysis, Wiley, Vol. 3, No. 2 ( 2011-02), p. 116-131
Abstract:
The charge‐transfer (CT) interactions between the electron donor sulfasalazine (SS) and the acceptors 2,3‐dichloro‐5,6‐dicyano‐1,4‐benzoquinone (DDQ), p ‐chloranil (CHL), picric acid (PA) and iodine have been studied spectrophotometrically in CHCl 3 or CH 3 OH solutions. The formed solid CT complexes were also isolated and characterized through infrared, 1 H‐NMR, mass spectra as well as elemental and thermal analysis. The CT complexes were discussed in terms of formation constant (K CT ), molar extinction coefficient (ε CT ), standard free energy (ΔG°), oscillator strength ( f ), transition dipole moment (µ), resonance energy (R N ) and ionization potential (I D ). The stoichiometry of these complexes was found to be 1:1 molar ratio and having the formulae [(SS)(DDQ)], [(SS)(CHL)] , [(SS)(PA)] and [(SS) 2 I] + · I 3 − , respectively. The charge transfer interaction was successfully applied to the determination of SS drug using mentioned σ and π‐acceptors also, the results obtained herein are satisfactory for estimation of SS compound in the pharmaceutical form. Copyright © 2010 John Wiley & Sons, Ltd.
Type of Medium:
Online Resource
ISSN:
1942-7603
,
1942-7611
Language:
English
Publisher:
Wiley
Publication Date:
2011
detail.hit.zdb_id:
2462336-2
detail.hit.zdb_id:
2462344-1
SSG:
15,3
SSG:
31
