In:
Chirality, Wiley, Vol. 23, No. 1E ( 2011-01)
Abstract:
Two new types of methylcalix[4]resorcinarene‐bonded stationary phases, (3‐( C ‐methylcalix[4]resorcinarene)‐2‐hydroxypropoxy) ‐propylsilyl‐appended silica particles ( MCR‐HPS ) and bromoacetate‐substituted MCR‐HPS particles ( BAMCR‐HPS ), have been synthesized and used as chiral stationary phases for high‐performance liquid chromatography (HPLC) for the first time. The synthetic stationary phases are characterized by means of elemental analysis and Fourier‐transform infrared spectroscopy. The chromatographic behavior of MCR‐HPS and BAMCR‐HPS was studied with several disubstituted benzenes and some chiral drug compounds under both normal phase and reversed‐phase conditions. The results show that MCR‐HPS has excellent selectivity for the separation of aromatic positional isomers and BAMCR‐HPS exhibits excellent performance for separation of enantiomers of chiral compounds. Chirality, 2011. © 2011 Wiley Periodicals, Inc.
Type of Medium:
Online Resource
ISSN:
0899-0042
,
1520-636X
Language:
English
Publisher:
Wiley
Publication Date:
2011
detail.hit.zdb_id:
1011639-4
detail.hit.zdb_id:
2001237-8
SSG:
12
SSG:
15,3