In:
Annals of Neurology, Wiley, Vol. 75, No. 6 ( 2014-06), p. 964-966
Abstract:
Behavioral, electrophysiological, and imaging data reveal impaired visual processing and altered retinal morphology in Parkinson disease. Are visual changes epiphenomena? We report the presence of misfolded α‐synuclein in the retina, not hitherto shown, in discrete retinal neurons within the inner retina. They demonstrate the histopathology that may underlie impaired vision and retinal remodeling in Parkinson disease. Furthermore, the histological localization of α‐synuclein gives clues to the nonsynaptic mode of α‐synuclein propagation. ANN NEUROL 2014;75:964–966
Type of Medium:
Online Resource
ISSN:
0364-5134
,
1531-8249
Language:
English
Publisher:
Wiley
Publication Date:
2014
detail.hit.zdb_id:
80362-5
detail.hit.zdb_id:
2037912-2