In:
Alzheimer's & Dementia, Wiley, Vol. 17, No. 10 ( 2021-10), p. 1610-1618
Abstract:
Facing considerable challenges associated with aging and dementia, China urgently needs an evidence‐based health‐care system for prevention and management of dementia. The Beijing Aging Brain Rejuvenation Initiative (BABRI) is a community‐based cohort study initiated in 2008 that focuses on asymptomatic stages of dementia, aims to develop community‐based prevention strategies for cognitive impairment, and provides a platform for scientific research and clinical trials. Thus far, BABRI has recruited 10,255 participants (aged 50 and over, 60.3% female), 2021 of whom have been followed up at least once at a 2‐ or 3‐year interval. This article presents aims and study design of BABRI; summarizes preliminary behavioral and neuroimaging findings on mild cognitive impairment (MCI) and results of clinical trials on MCI; and discusses issues concerning early prevention in community, MCI diagnosis methods, and applications of database of aging and dementia. BABRI is proposed to build a systematic framework on brain health in old age.
Type of Medium:
Online Resource
ISSN:
1552-5260
,
1552-5279
Language:
English
Publisher:
Wiley
Publication Date:
2021
detail.hit.zdb_id:
2201940-6