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  • American Physiological Society  (14)
  • 1955-1959  (14)
  • 1
    Online Resource
    Online Resource
    American Physiological Society ; 1958
    In:  American Journal of Physiology-Legacy Content Vol. 195, No. 2 ( 1958-10-31), p. 354-356
    In: American Journal of Physiology-Legacy Content, American Physiological Society, Vol. 195, No. 2 ( 1958-10-31), p. 354-356
    Abstract: Following administration of uranium parenterally into rats in an acute dose, the increase in protein excretion consisted not only of an increase in the normally occurring albumin but to a greater extent an increase in the various globulins. At the height of proteinuria, the electrophoretic pattern of the excreted proteins strongly resembled the pattern of the serum proteins. The appearance of these serum-like urinary proteins suggests a defect in the glomerulus filtration apparatus and provides further evidence that the glomerulus, as well as the tubule, is altered by uranium administration.
    Type of Medium: Online Resource
    ISSN: 0002-9513
    RVK:
    RVK:
    Language: English
    Publisher: American Physiological Society
    Publication Date: 1958
    detail.hit.zdb_id: 1477334-X
    detail.hit.zdb_id: 2065807-2
    detail.hit.zdb_id: 1477287-5
    detail.hit.zdb_id: 1477308-9
    detail.hit.zdb_id: 1477297-8
    detail.hit.zdb_id: 1477331-4
    detail.hit.zdb_id: 1477300-4
    detail.hit.zdb_id: 1477329-6
    SSG: 12
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  • 2
    Online Resource
    Online Resource
    American Physiological Society ; 1956
    In:  Journal of Applied Physiology Vol. 9, No. 1 ( 1956-07), p. 1-4
    In: Journal of Applied Physiology, American Physiological Society, Vol. 9, No. 1 ( 1956-07), p. 1-4
    Type of Medium: Online Resource
    ISSN: 8750-7587 , 1522-1601
    RVK:
    RVK:
    Language: English
    Publisher: American Physiological Society
    Publication Date: 1956
    detail.hit.zdb_id: 1404365-8
    SSG: 12
    SSG: 31
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  • 3
    Online Resource
    Online Resource
    American Physiological Society ; 1956
    In:  Journal of Neurophysiology Vol. 19, No. 6 ( 1956-11-01), p. 573-595
    In: Journal of Neurophysiology, American Physiological Society, Vol. 19, No. 6 ( 1956-11-01), p. 573-595
    Type of Medium: Online Resource
    ISSN: 0022-3077 , 1522-1598
    RVK:
    Language: English
    Publisher: American Physiological Society
    Publication Date: 1956
    detail.hit.zdb_id: 80161-6
    detail.hit.zdb_id: 1467889-5
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  • 4
    Online Resource
    Online Resource
    American Physiological Society ; 1956
    In:  American Journal of Physiology-Legacy Content Vol. 186, No. 3 ( 1956-09-01), p. 453-459
    In: American Journal of Physiology-Legacy Content, American Physiological Society, Vol. 186, No. 3 ( 1956-09-01), p. 453-459
    Abstract: The dependence of the ratio of the radioiodide concentrations in thyroid gland and serum ( T/S) on the serum iodide concentration for fixed serum thiocyanate concentrations was investigated in C 3 H mice. The empirical equation (See PDF for Equation) where [SCN – ] and [I – ] are the serum thiocyanate and iodide concentrations in mg %, fitted the data within the limits of experimental error. Interpretation of the empirical equation was based on simple adsorption and active transport models of the iodide concentrating mechanism. The inhibition by thiocyanate of the thyroidal iodide concentrating mechanism appears to be competitive.
    Type of Medium: Online Resource
    ISSN: 0002-9513
    RVK:
    RVK:
    Language: English
    Publisher: American Physiological Society
    Publication Date: 1956
    detail.hit.zdb_id: 1477334-X
    detail.hit.zdb_id: 2065807-2
    detail.hit.zdb_id: 1477287-5
    detail.hit.zdb_id: 1477308-9
    detail.hit.zdb_id: 1477297-8
    detail.hit.zdb_id: 1477331-4
    detail.hit.zdb_id: 1477300-4
    detail.hit.zdb_id: 1477329-6
    SSG: 12
    Location Call Number Limitation Availability
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  • 5
    Online Resource
    Online Resource
    American Physiological Society ; 1959
    In:  American Journal of Physiology-Legacy Content Vol. 196, No. 6 ( 1959-06-01), p. 1340-1345
    In: American Journal of Physiology-Legacy Content, American Physiological Society, Vol. 196, No. 6 ( 1959-06-01), p. 1340-1345
    Abstract: The nature of the depressor substance in extracts of rabbit kidneys was investigated. In addition to lowering blood pressure the extracts were found to inhibit motility of isolated rabbit intestine, stimulate isolated uterus, cause blanching of rabbit and rat kidney, cause slowing of the heart and prolongation of the P-R interval. These same effects are produced by adenosine and its nucleotides. The depressor substance was shown not to be acetylcholine, choline, histamine or kallikrein. Analysis of the kidney tissue extract by means of column chromatography and measurement of ultraviolet absorption revealed the presence of approximately equal amounts of adenosine mono-, di- and triphosphate as well as lesser amounts of other nucleotides. The amounts of the adenosine derivatives present are sufficient to account for the degree of blood pressure lowering produced by the unfractionated kidney extract. On the basis of this quantitative agreement and the pharmacological effects noted it is concluded that the depressor action of rabbit kidney extract is due to its content of adenosine nucleotides.
    Type of Medium: Online Resource
    ISSN: 0002-9513
    RVK:
    RVK:
    Language: English
    Publisher: American Physiological Society
    Publication Date: 1959
    detail.hit.zdb_id: 1477334-X
    detail.hit.zdb_id: 2065807-2
    detail.hit.zdb_id: 1477287-5
    detail.hit.zdb_id: 1477308-9
    detail.hit.zdb_id: 1477297-8
    detail.hit.zdb_id: 1477331-4
    detail.hit.zdb_id: 1477300-4
    detail.hit.zdb_id: 1477329-6
    SSG: 12
    Location Call Number Limitation Availability
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  • 6
    Online Resource
    Online Resource
    American Physiological Society ; 1955
    In:  American Journal of Physiology-Legacy Content Vol. 181, No. 3 ( 1955-06-01), p. 669-674
    In: American Journal of Physiology-Legacy Content, American Physiological Society, Vol. 181, No. 3 ( 1955-06-01), p. 669-674
    Type of Medium: Online Resource
    ISSN: 0002-9513
    RVK:
    RVK:
    Language: English
    Publisher: American Physiological Society
    Publication Date: 1955
    detail.hit.zdb_id: 1477334-X
    detail.hit.zdb_id: 2065807-2
    detail.hit.zdb_id: 1477287-5
    detail.hit.zdb_id: 1477308-9
    detail.hit.zdb_id: 1477297-8
    detail.hit.zdb_id: 1477331-4
    detail.hit.zdb_id: 1477300-4
    detail.hit.zdb_id: 1477329-6
    SSG: 12
    Location Call Number Limitation Availability
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  • 7
    Online Resource
    Online Resource
    American Physiological Society ; 1955
    In:  American Journal of Physiology-Legacy Content Vol. 181, No. 1 ( 1955-03-31), p. 30-34
    In: American Journal of Physiology-Legacy Content, American Physiological Society, Vol. 181, No. 1 ( 1955-03-31), p. 30-34
    Type of Medium: Online Resource
    ISSN: 0002-9513
    RVK:
    RVK:
    Language: English
    Publisher: American Physiological Society
    Publication Date: 1955
    detail.hit.zdb_id: 1477334-X
    detail.hit.zdb_id: 2065807-2
    detail.hit.zdb_id: 1477287-5
    detail.hit.zdb_id: 1477308-9
    detail.hit.zdb_id: 1477297-8
    detail.hit.zdb_id: 1477331-4
    detail.hit.zdb_id: 1477300-4
    detail.hit.zdb_id: 1477329-6
    SSG: 12
    Location Call Number Limitation Availability
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  • 8
    Online Resource
    Online Resource
    American Physiological Society ; 1958
    In:  American Journal of Physiology-Legacy Content Vol. 193, No. 3 ( 1958-06-01), p. 573-575
    In: American Journal of Physiology-Legacy Content, American Physiological Society, Vol. 193, No. 3 ( 1958-06-01), p. 573-575
    Abstract: In the tissues of the peritoneal cavity the mast cell appears to be the only cell capable of releasing histamine. Protamine sulfate and toluidine blue in certain concentrations in Tyrode's solution when injected intraperitoneally elicit the liberation of measurable amounts of histamine into the peritoneal fluid. Repeated injections of these substances cause repeated liberation of histamine. No visible changes in the mesenteric mast cells follow this treatment. It is concluded that secretion by the mast cell does not require cell disruption and death as much of the literature indicates but is merocrine in nature. The mast cell appears to be an endocrine cell which can continuously elaborate and release histamine in in response to appropriate stimulation.
    Type of Medium: Online Resource
    ISSN: 0002-9513
    RVK:
    RVK:
    Language: English
    Publisher: American Physiological Society
    Publication Date: 1958
    detail.hit.zdb_id: 1477334-X
    detail.hit.zdb_id: 2065807-2
    detail.hit.zdb_id: 1477287-5
    detail.hit.zdb_id: 1477308-9
    detail.hit.zdb_id: 1477297-8
    detail.hit.zdb_id: 1477331-4
    detail.hit.zdb_id: 1477300-4
    detail.hit.zdb_id: 1477329-6
    SSG: 12
    Location Call Number Limitation Availability
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  • 9
    Online Resource
    Online Resource
    American Physiological Society ; 1955
    In:  American Journal of Physiology-Legacy Content Vol. 181, No. 1 ( 1955-03-31), p. 79-82
    In: American Journal of Physiology-Legacy Content, American Physiological Society, Vol. 181, No. 1 ( 1955-03-31), p. 79-82
    Type of Medium: Online Resource
    ISSN: 0002-9513
    RVK:
    RVK:
    Language: English
    Publisher: American Physiological Society
    Publication Date: 1955
    detail.hit.zdb_id: 1477334-X
    detail.hit.zdb_id: 2065807-2
    detail.hit.zdb_id: 1477287-5
    detail.hit.zdb_id: 1477308-9
    detail.hit.zdb_id: 1477297-8
    detail.hit.zdb_id: 1477331-4
    detail.hit.zdb_id: 1477300-4
    detail.hit.zdb_id: 1477329-6
    SSG: 12
    Location Call Number Limitation Availability
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  • 10
    Online Resource
    Online Resource
    American Physiological Society ; 1959
    In:  American Journal of Physiology-Legacy Content Vol. 197, No. 3 ( 1959-09-01), p. 575-579
    In: American Journal of Physiology-Legacy Content, American Physiological Society, Vol. 197, No. 3 ( 1959-09-01), p. 575-579
    Abstract: This study investigated the effect of a number of factors on the inhibition of thrombin by the anticoagulant fraction of incubated fibrinogen (AFIF). Heating above 46°C reduces and at 55°C completely abolishes the thrombin-inhibiting activity of AFIF. The prolongation of the thrombin time of fibrinogen by AFIF is proportional to the pH of the reaction mixture, while that of plasma tends to level off beyond pH 7.5. Calcium and magnesium up to a concentration of 10 mm shorten the thrombin time of both plain fibrinogen and fibrinogen mixed with AFIF in a proportional manner. AFIF partially inhibits the thrombin time reducing property of protamine on fibrinogen. Related probably to this is the observation that AFIF and serum protect purified fibrinogen from precipitation by protamine. The inhibitory effect of AFIF on the action of thrombin on fibrinogen was found to be competitive in nature. The hydrolysis of tosylarginine methylester by thrombin was shown to be unaffected by AFIF. The properties of the anticoagulant studied did not allow its identification with heparin.
    Type of Medium: Online Resource
    ISSN: 0002-9513
    RVK:
    RVK:
    Language: English
    Publisher: American Physiological Society
    Publication Date: 1959
    detail.hit.zdb_id: 1477334-X
    detail.hit.zdb_id: 2065807-2
    detail.hit.zdb_id: 1477287-5
    detail.hit.zdb_id: 1477308-9
    detail.hit.zdb_id: 1477297-8
    detail.hit.zdb_id: 1477331-4
    detail.hit.zdb_id: 1477300-4
    detail.hit.zdb_id: 1477329-6
    SSG: 12
    Location Call Number Limitation Availability
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