Description:    Analysis of published data on the stability of Ln 2+ and An 2+ in deaerated aqueous solutions and in solutions of tetrahydrofuran, hexamethylphosphoric triamide, and other solvents shows that the oxidation, following a first-order rate law, involves thermal excitation of the bivalent ion, fast formation of a complex of the excited and unexcited ions (excimer), and its decomposition into fragments, i.e.,. Ln 3+ or An 3+ and H 2 . Content Type Journal Article Pages 452-454 DOI 10.1134/S1066362212050050 Authors V. P. Shilov, Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Leninskii pr. 31, block 4, Moscow, 119071 Russia A. V. Gogolev, Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Leninskii pr. 31, block 4, Moscow, 119071 Russia A. M. Fedoseev, Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Leninskii pr. 31, block 4, Moscow, 119071 Russia Journal Radiochemistry Online ISSN 1608-3288 Print ISSN 1066-3622 Journal Volume Volume 54 Journal Issue Volume 54, Number 5

Description:    A simple method was developed for labeling N -{4-[(3-chloro-4-fluorophenyl)amino]quinazolin-6-yl}-3-bromopropionamide, an EGFR inhibitor, with radioactive iodine via nucleophilic iododebromination. The factors affecting the radiochemical yield of 125 I-EGFR such as reaction medium, substrate concentration, CuCl concentration, and temperature were examined. Reducing agents such as ascorbic acid, SnCl 2 , and Na 2 S 2 O 5 were used to prevent disproportionation. The radiochemical yield and purity of the labeled product were determined by TLC and HPLC. Content Type Journal Article Pages 497-500 DOI 10.1134/S1066362212050141 Authors N. Farouk, Labelled Compounds Department, Radioisotope Production and Radioactive Sources Division, Hot Laboratories Centre, Atomic Energy Authority, P.O. Box 13759, Cairo, Egypt H. E. Ramadan, Labelled Compounds Department, Radioisotope Production and Radioactive Sources Division, Hot Laboratories Centre, Atomic Energy Authority, P.O. Box 13759, Cairo, Egypt M. A. El-Amir, Labelled Compounds Department, Radioisotope Production and Radioactive Sources Division, Hot Laboratories Centre, Atomic Energy Authority, P.O. Box 13759, Cairo, Egypt Journal Radiochemistry Online ISSN 1608-3288 Print ISSN 1066-3622 Journal Volume Volume 54 Journal Issue Volume 54, Number 5

Description:    Zirconyl molybdopyrophosphate (ZMPP) inorganic ion exchanger was synthesized by precipitation and used for preparing a 60 Co sealed source. The distribution coefficient of 60 Co(II) ions on ZMPP was determined in relation to the HCl concentration. The saturation capacity of ZMPP for 60 Co(II) was determined by the batch method to be 1.33 mmol g −1 . The ZMPP ion exchanger was loaded with 60 Co radionuclides by equilibrating a 60 Co solution with 1 g of ZMPP at pH 5 (HCl) for 48 h at 25 ± 1°C. A sealed source of 1.04 μCi 60 Co (±5%) was prepared by packing 100 mg of the loaded matrix in the cylindrical cavity of a Chinese Artelone capsule. After radiometric standardization and encapsulation, the sealed source was submitted to quality control tests and finally checked radiometrically before release to the local market for calibration of radiation measurements and identification instruments. Content Type Journal Article Pages 492-496 DOI 10.1134/S106636221205013X Authors S. A. Shady, Nuclear Fuel Technology Department, Hot Laboratories Center, Atomic Energy Authority, P.O. 13759, Cairo, Egypt Journal Radiochemistry Online ISSN 1608-3288 Print ISSN 1066-3622 Journal Volume Volume 54 Journal Issue Volume 54, Number 5

Description:    A method was suggested for studying the dynamic sorption properties of ferrocyanide sorbents toward Cs radionuclides by analyzing the radiocesium distribution in the solid phase of the sorbent. The dynamic sorption characteristics are determined by measuring the activity of successive sorbent layers after passing definite volumes of the solution. The method is efficient in analysis of the stability of various sorbents in liquid media. The sorption characteristics of the following ferrocyanide sorbents were examined: Termoksid-35 (nickel-potassium ferrocyanide on zirconium hydroxide), FNS-2 (nickel-potassium ferrocyanide on silica), and FS-2 (copper-potassium ferrocyanide on silica). In alkaline solutions, Termoksid-35 is the most stable. The effect of oxalic acid on the activity distribution in a ferrocyanide sorbent bed was studied. In alkaline solutions containing oxalic acid, copper ferrocyanide (FS-2) is the least stable. At the same time, at low pH values and in the absence of oxalic acid, it is preferable to use sorbents based on copper ferrocyanides. Content Type Journal Article Pages 483-488 DOI 10.1134/S1066362212050116 Authors A. M. Egorin, Institute of Chemistry, Far-Eastern Division, Russian Academy of Sciences, pr. 100-Letiya Vladivostoka 159, Vladivostok, 690022 Russia V. A. Avramenko, Institute of Chemistry, Far-Eastern Division, Russian Academy of Sciences, pr. 100-Letiya Vladivostoka 159, Vladivostok, 690022 Russia Journal Radiochemistry Online ISSN 1608-3288 Print ISSN 1066-3622 Journal Volume Volume 54 Journal Issue Volume 54, Number 5

Description:    Published data on precision spectorphotometric determination of U, Th, Pu, and other elements of the nuclear fuel cycle in solutions on a two-channel analyzer with the relative random uncertainty S r = 0.1–0.2% are summarized. The method was used for certification and fabrication of Pu and U total weight fraction standards for mass spectrometer calibration. New data on precision determination of U, Ru, Er, Gd, Sm, Re, and Tc on serial Shimadzu UV devices in the photometric mode with the relative random uncertainty S r = 0.02–0.04% are presented. The relative total uncertainty that can be attained with the spectrophotometric method is as low as 0.03–0.05%, which makes this method competitive with other precision methods used. Content Type Journal Article Pages 419-430 DOI 10.1134/S1066362212050013 Authors S. A. Nikitina, Khlopin Radium Institute, Research and Production Association, Federal State Unitary Enterprise, 2-i Murinskii pr. 28, St. Petersburg, 194021 Russia T. D. Gogoleva, Khlopin Radium Institute, Research and Production Association, Federal State Unitary Enterprise, 2-i Murinskii pr. 28, St. Petersburg, 194021 Russia S. N. Voronina, Khlopin Radium Institute, Research and Production Association, Federal State Unitary Enterprise, 2-i Murinskii pr. 28, St. Petersburg, 194021 Russia Journal Radiochemistry Online ISSN 1608-3288 Print ISSN 1066-3622 Journal Volume Volume 54 Journal Issue Volume 54, Number 5

Description:    Interaction of actinides(IV) with hydroxyisobutyric acid (HHIB) in aqueous solutions and in the course of crystallization of solid compounds was studied. The complexes ML n (4- n )+ (M = U, Np, Pu; L − is hydroxyisobutyrate anion; n = 1, 2, 3) exist in solution. Their apparent stepwise stability constants K ′ i were measured, and the overall concentration stability constants β 3 of the complexes ML 3 + were calculated. For U(IV) and Np(IV), logβ 3 is close to 13.3–13.4, and for Pu(IV), logβ 3 = 14.5 ± 0.9 (ionic strength I = 0.1–0.3). In the course of crystallization in air, complexes of U(IV) with hydroxyisobutyric acid, as well as those with citric acid, undergo oxidative degradation, which can be accompanied by complete oxidation of U(IV). The crystalline compounds formed in the process are oxalates of U(IV) or U(VI). The complexation of Np(V) with HHIB was studied. NpO 2 + forms with HHIB the complexes NpO 2 L and NpO 2 L 2 − . Their concentration stability constants are log K 1 = 2.04 ± 0.15 and log K 2 = 0.71 ± 0.10 ( I = 0.4), i.e., logβ 2 = 2.75 ± 0.25. Content Type Journal Article Pages 443-451 DOI 10.1134/S1066362212050049 Authors A. M. Fedoseev, Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Leninskii pr. 31, block 4, Moscow, 119071 Russia M. S. Grigor’ev, Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Leninskii pr. 31, block 4, Moscow, 119071 Russia A. B. Yusov, Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Leninskii pr. 31, block 4, Moscow, 119071 Russia Journal Radiochemistry Online ISSN 1608-3288 Print ISSN 1066-3622 Journal Volume Volume 54 Journal Issue Volume 54, Number 5

Description:    Decomposition of hydroxylamine in HNO 3 solutions containing 350 to 920 g l −1 U(VI) was studied. In the absence of fission and corrosion products (Zr, Pd, Tc, Mo, Fe, etc.), hydroxylamine is stable for no less than 6 h at [HNO 3 ] 〈 1 M and 60°C. In the presence of these products, the stability of hydroxylamine appreciably decreases. The reduction of Pu(IV) and Np(VI) with hydroxylamine in aqueous 0.33 and 0.5 M HNO 3 solutions containing 850 g l −1 U(VI) and fission and corrosion products at 60°C was studied. Np(VI) is rapidly reduced to Np(V), after which Np(V) is partially reduced to Np(IV). The rate of the latter reaction in such solutions is considerably higher than the rate of the Np(V) reduction with hydroxylamine in HNO 3 solutions without U(VI). At [HNO 3 ] = 0.33 M, the use of hydroxylamine results in the conversion of Pu to Pu(III) and of Np to a Np(IV,V) mixture, whereas at [HNO 3 ] = 0.5 M the final products are Pu(IV) and Np(V). Content Type Journal Article Pages 459-464 DOI 10.1134/S1066362212050074 Authors V. I. Marchenko, Bochvar High-Tech Institute of Inorganic Materials, Public Joint-Stock Company, ul. Rogova 5a, Moscow, 123060 Russia K. N. Dvoeglazov, Bochvar High-Tech Institute of Inorganic Materials, Public Joint-Stock Company, ul. Rogova 5a, Moscow, 123060 Russia O. A. Savilova, Bochvar High-Tech Institute of Inorganic Materials, Public Joint-Stock Company, ul. Rogova 5a, Moscow, 123060 Russia V. I. Volk, Bochvar High-Tech Institute of Inorganic Materials, Public Joint-Stock Company, ul. Rogova 5a, Moscow, 123060 Russia Journal Radiochemistry Online ISSN 1608-3288 Print ISSN 1066-3622 Journal Volume Volume 54 Journal Issue Volume 54, Number 5

Description:    Extraction of microamounts of U(VI), Th(IV), and REE(III) from HNO 3 solutions in the form of complexes with 1,7-bis(dibutylcarbamoyl)-1,7-bis(diphenylphosphinyl)heptane ( I ) was studied. The influence of the composition of the aqueous and organic phases on the extraction efficiency was considered, and the stoichiometry of the extractable complexes was determined. The extraction of metal ions is considerably enhanced in the presence of an ionic liquid. In neutral media, compound I exhibits higher extraction ability than does its mono analog, (dibutylcarbamoylmethyl)diphenylphosphine oxide ( II ). Content Type Journal Article Pages 477-482 DOI 10.1134/S1066362212050104 Authors A. N. Turanov, Institute of Solid State Physics, Russian Academy of Sciences, ul. Akad. Osip’yana 2, Chernogolovka, Moscow oblast, 142432 Russia V. K. Karandashev, Institute of Technological Problems of Microelectronics and Ultrapure Materials, Russian Academy of Sciences, ul. Akad. Osip’yana 6, Chernogolovka, Moscow oblast, 142432 Russia A. N. Yarkevich, Institute of Physiologically Active Substances, Russian Academy of Sciences, Severnyi proezd 1, Chernogolovka, Moscow oblast, 142432 Russia Journal Radiochemistry Online ISSN 1608-3288 Print ISSN 1066-3622 Journal Volume Volume 54 Journal Issue Volume 54, Number 5

Description:    Products of decomposition of the UO 2 (NO 3 ) 2 ·6H 2 O + Fe(NO 3 ) 3 ·9H 2 O mixture under the action of microwave radiation (MWR) were studied by thermal gravimetric, X-ray phase, and chemical analyses. The results obtained were compared to the published data for various U and Fe compounds. The final products of decomposition of the UO 2 (NO 3 ) 2 ·6H 2 O + Fe(NO 3 ) 3 ·9H 2 O mixture under the action of MWR for 3–5 min (the maximal temperature of the process, equal to 140–150°, is attained within 2–3 min of irradiation), apart from gaseous products, are UO 2 (OH)NO 3 , UO 3 , and Fe 2 O 3 . The action of MWR on the UO 2 (NO 3 ) 2 ·6H 2 O + Fe(NO 3 ) 3 ·9H 2 O mixture under the examined conditions does not lead to the formation of uranyl ferrite. Content Type Journal Article Pages 465-472 DOI 10.1134/S1066362212050086 Authors S. A. Kulyukhin, Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Leninskii pr. 31, block 4, Moscow, 119071 Russia A. N. Kamenskaya, Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Leninskii pr. 31, block 4, Moscow, 119071 Russia Journal Radiochemistry Online ISSN 1608-3288 Print ISSN 1066-3622 Journal Volume Volume 54 Journal Issue Volume 54, Number 5

Description:    An L -carnitine derivative labeled with 99 m Tc was prepared. It is effective in tumor imaging. The labeling was done using SnCl 2 as a reducing agent. The optimum conditions required to label 25 μg of L -carnitine were as follows: 100 μg of SnCl 2 , 30 min reaction time, room temperature, pH 7 (0.5 M phosphate buffer). The radiochemical purity of the labeled compound was determined by paper chromatography. The yield was about 93%. About 2.5 × 10 6 Ehrlich ascites carcinoma (EAC) cells were injected intraperitoneally to produce ascites and intramuscularly in the right thigh to produce solid tumor in female mice. Biodistribution studies were carried out by injecting a solution of 99 m Tc- L -carnitine into normal and tumor-bearing mice. The uptake in ascites and in solid tumor was over 5% of the injected dose per gram tissue at 4 h post injection. These data revealed localization of the tracer in the tumor tissues with high percentage sufficient to use 99 m Tc- L -carnitine as a promising tool for diagnosis of tumor. Content Type Journal Article Pages 407-411 DOI 10.1134/S1066362212040170 Authors I. T. Ibrahim, Labelled Compounds Department, Radioisotopes Production and Radioactive Sources Division, Hot Laboratories Center, Atomic Energy Authority, P.O. Box 13759, Cairo, Egypt K. M. Attallah, Department of Pharmaceutics, Faculty of Pharmacy, Umm El-Qurah University, Makkah, Saudi Arabia Journal Radiochemistry Online ISSN 1608-3288 Print ISSN 1066-3622 Journal Volume Volume 54 Journal Issue Volume 54, Number 4