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An Exact Hypergraph Matching algorithm for posture identification in embryonic C. elegans

Fig 1

Seam cells are used to recover C. elegans posture in high spatial resolution, low temporal resolution imaging.

A: Manually identified seam cell nuclei from an imaged C. elegans embryo. The cells form in pairs; they are labelled anterior to posterior: H0, H1, …, V6, T. The identification of all seam cells reveals the embryo’s posture. Natural cubic splines through the left and right-side seam cells estimate the coiled embryo’s body. The left image depicts identified nuclei connected to outline the embryo; splines are used to untwist the embryo, generating the remapped straightened points in the diagram on the right. B: Labelled nuclear coordinates from a sequence of four images. The embryo repositions in the five minute intervals between images, causing failure of traditional point-set matching approaches.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0277343.g001